Antipsychotic drugs were introduced in the early 50s on the basis of clinical observations in
patients with schizophrenia. Experimental studies later revealed that antagonism at the D2 …

This study evaluated the performance of the Biograph Vision digital PET/CT system
according to the NEMA NU 2-2012 standard (published by the National Electrical …

Purpose: Approximately one-third of patients with non–small cell lung cancer (NSCLC)
harboring tumors with EGFR-tyrosine kinase inhibitor (TKI)-sensitizing mutations (EGFRm) …

Rationale This review attempts to summarize the current status in relation to the use of
positron emission tomography (PET) imaging in the assessment of synaptic concentrations …

Impaired mitochondrial function, oxidative stress and formation of excessive levels of
reactive oxygen species play a key role in neurodegeneration in Parkinson's disease …

Pioneered with the invention of 11C-Pittsburgh compound B, amyloid-β imaging using PET
has facilitated research in Alzheimer disease (AD). This imaging approach has promise for …

The glutamate N-methyl-d-aspartate receptor antagonist ketamine has a rapid
antidepressant effect. Despite large research efforts, ketamine's mechanism of action in …

Electroconvulsive therapy (ECT) is a potent therapy in severe treatment-refractory
depression. Although commonly applied in psychiatric clinical routine since decades, the …

Several lines of evidence are indicative of a role for immune activation in the
pathophysiology of schizophrenia. Nevertheless, studies using positron emission …

The purpose of this study was to quantify any differences between the SUVs of 89Zr immuno-
PET scans obtained using a PET/CT system with a long axial field of view (LAFOV; Biograph …