The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …

AIMS: In this review metabolomics is introduced in historic perspective, with key platforms
and bioinformatics methodologies described. An overview is provided covering recent …

Calorie restriction (CR) is a dietary regimen that reduces calorie intake without incurring
malnutrition or a reduction in essential nutrients. It has long been recognized as a natural …

The modern food system feeds six billion people with remarkable diversity, safety, and
nutrition. Yet, the current rise in diet-related diseases is compromising health and devaluing …

Background Using metabolomics technique to analyze the response to a dietary intervention
generates valuable information concerning the effects of the prescribed diet on metabolic …

The application of metabolomics in nutritional research may be a useful tool to analyse and
predict the response to a dietary intervention. The aim of this study was to examine …

The field of lipidomics is providing nutritional science a more comprehensive view of lipid
intermediates. Lipidomics research takes advantage of the increase in accuracy and …

Lifestyle-based weight loss interventions frequently demonstrate long-term inefficiency and
weight regain. Identification of underlying mechanisms and predictors to identify subjects …

Background The nutrigenomics, overweight/obesity and weight management trial (NOW
Trial) is a pragmatic randomized controlled trial of community-dwelling adults recruited from …

The amount of weight loss in obese children during lifestyle intervention differs strongly
between individuals. The metabolic processes underlying this variability are largely …