Late-stage C–H functionalization of azines

CM Josephitis, HMH Nguyen, A McNally - Chemical reviews, 2023 - ACS Publications
Azines, such as pyridines, quinolines, pyrimidines, and pyridazines, are widespread
components of pharmaceuticals. Their occurrence derives from a suite of physiochemical …

[HTML][HTML] Recent advances in visible light-activated radical coupling reactions triggered by (i) ruthenium,(ii) iridium and (iii) organic photoredox agents

JD Bell, JA Murphy - Chemical Society Reviews, 2021 - pubs.rsc.org
Photoredox chemistry with organic or transition metal agents has been reviewed in earlier
years, but such is the pace of progress that we will overlap very little with earlier …

Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds

R Cannalire, S Pelliccia, L Sancineto… - Chemical Society …, 2021 - pubs.rsc.org
The late stage functionalization (LSF) of complex biorelevant compounds is a powerful tool
to speed up the identification of structure–activity relationships (SARs) and to optimize …

Visible light promoted cross-dehydrogenative coupling: a decade update

AK Bagdi, M Rahman, D Bhattacherjee… - Green …, 2020 - pubs.rsc.org
The visible light promoted cross-dehydrogenative coupling reaction has emerged as an
excellent strategy for the direct formation of C–C/C–heteroatom bonds from simple …

Microfluidic electrochemistry for single-electron transfer redox-neutral reactions

Y Mo, Z Lu, G Rughoobur, P Patil, N Gershenfeld… - Science, 2020 - science.org
Electrochemistry offers opportunities to promote single-electron transfer (SET) redox-neutral
chemistries similar to those recently discovered using visible-light photocatalysis but without …

Scalable Photoelectrochemical Dehydrogenative Cross‐Coupling of Heteroarenes with Aliphatic C− H Bonds

P Xu, PY Chen, HC Xu - Angewandte Chemie International …, 2020 - Wiley Online Library
Heteroarenes are structural motifs found in many bioactive compounds and functional
materials. Dehydrogenative cross‐coupling of heteroarenes with aliphatic C− H bonds …

Enroute sustainability: metal free C–H bond functionalisation

S Roy, S Panja, SR Sahoo, S Chatterjee… - Chemical Society …, 2023 - pubs.rsc.org
The term “C–H functionalisation” incorporates C–H activation followed by its transformation.
In a single line, this can be defined as the conversion of carbon–hydrogen bonds into …

Organophotoelectrocatalytic C (sp 2)–H alkylation of heteroarenes with unactivated C (sp 3)–H compounds

Q Wan, XD Wu, ZW Hou, Y Ma, L Wang - Chemical Communications, 2024 - pubs.rsc.org
An organophotoelectrocatalytic method for the C (sp2)–H alkylation of heteroarenes with
unactivated C (sp3)–H compounds through dehydrogenation cross-coupling has been …

Photoinduced, metal-and photosensitizer-free decarboxylative C–H (amino) alkylation of heteroarenes in a sustainable solvent

J Xu, C Liang, J Shen, Q Chen, W Li, P Zhang - Green Chemistry, 2023 - pubs.rsc.org
Herein, a metal-and photosensitizer-free protocol has been developed for decarboxylative C–
H (amino) alkylation of heteroarenes using carboxylic acids as the (amino) alkylating …

Electrophotocatalysis for Organic Synthesis

MC Lamb, KA Steiniger, LK Trigoura, J Wu… - Chemical …, 2024 - ACS Publications
Electrocatalysis and photocatalysis have been the focus of extensive research efforts in
organic synthesis in recent decades, and these powerful strategies have provided a wealth …