MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …

MicroRNAs (miRNAs) are endogenous 22 nt non-coding RNAs that target mRNAs for
cleavage or translational repression. Numerous miRNAs regulate programmed cell death …

Objective Alcoholic liver disease (ALD) is a leading cause of death among chronic liver
diseases. However, its pathogenesis has not been completely established. MicroRNAs …

Colorectal cancer (CRC) is the third leading cause of cancer death in the world, and its
incidence is rising in developing countries. Treatment with 5-Fluorouracil (5-FU) is known to …

Apoptosis deficiency is one of the most important features observed in neoplastic diseases.
The Bcl-2 family is composed of a subset of proteins that act as decisive apoptosis …

Mesenchymal stromal/stem cells (MSCs) are clinically useful for cell-based therapy, but
concerns regarding their ability to replicate limit their human application. MSCs release …

Abstract miRNAs act as oncogenes or tumor suppressors in a wide variety of human
cancers, including prostate cancer (PCa). We found a severe and consistent downregulation …

Background Reliable prognostic biomarkers to distinguish indolent from aggressive prostate
cancer (PCa) are lacking. Many studies investigated microRNAs (miRs) as PCa prognostic …

Colorectal cancer (CRC) is known as the third common cancer worldwide and an important
public health problem in different populations. Several genetics and environmental risk …

Cross talk, mediated by exosomes, between normal stem cells and cancer stem cells
(CSCs) in the tumor microenvironment has been given less attention so far. In addition, no …