Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …

Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …

Diabetes is a chronic medical condition due to the lack of insulin or ineffective use of insulin.
In recent years, diabetes has become one of the rapidly growing chronic diseases, and it …

Abstract Rhodanine or 2‐Thioxothiazolidin‐4‐one is a privileged heterocyclic compound
offering a wide opportunity for structural modification, lead development, and modification. It …

Mycobacterium tuberculosis infections still pose a serious threat to human health.
Combination therapies are effective medical solutions to the problem. Mycobacterium …

Abstract Zinc metalloprotease 1 (Zmp1) is an extracellular enzyme, which has been found
essential for the intracellular survival and pathogenesis of Mycobacterium tuberculosis. In …

Asymmetric total synthesis of cyclotetradepsipeptide beauveamide A has been achieved for
the first time. A macrolactamization strategy involving two possible sites has been explored …

Abstract Mycobacterial zinc metalloprotease-1 (Zmp1) is an essential enzyme for
intracellular survival and pathogenicity of Mycobacterium tuberculosis. However, the exact …

Rhodanines are five-member heterocyclics having sulfur, nitrogen, and oxygen atoms in
their ring structure and exhibit potent as well as a broad range of pharmacological activities …

Background: Epidermal growth factor receptor (EGFR) is seen in almost all cases of non-
small cell lung cancer (NSCLC). As a result, targeting EGFR has become an attractive …