Bone tissue is a nanocomposite consisting of an organic and inorganic matrix, in which the
collagen component and the mineral phase are organized into complex and porous …

In severe tissue destruction, not only large number of cells are destroyed, but also the
extracellular matrix (ECM). The ECM is a three-dimensional (3D) network that provides …

The main aim of the present study was to fabricate 3D scaffold based on poly (l-lactic
acid)(PLLA)/Polycaprolactone (PCL) matrix polymer containing gelatin nanofibers (GNFs) …

Nanoclays, 2D layered mineral silicates, have been used for centuries and have retained a
prominent role in advancing materials science and technology. This class of materials has …

The fabrication of 3D scaffolds is under wide investigation in tissue engineering (TE)
because of its incessant development of new advanced technologies and the improvement …

The natural healing process of bone is impaired in the presence of tumors, trauma, or
inflammation, necessitating external assistance for bone regeneration. The limitations of …

Nanostructured polymer composites have gained significant attention in recent years for
their remarkable potential in bone and tissue regeneration. Moreover, with the integration of …

Porosity affects performance of scaffolds for bone tissue engineering both in vitro and in
vivo. Macropores (ie, pores with a diameter> 100 μm) are essential for cellular infiltration; …

Background: Cytotoxicity testing is a primary method to establish the safety of biomaterials,
eg, biocomposites. Biomaterials involve a wide range of medical materials, which are …

A 3D‐printed biodegradable hydrogel, consisting of alginate, gelatin, and freeze‐dried bone
allograft nanoparticles (npFDBA), is developed as a scaffold for enhancing cell adhesion …