Molecular typing has revolutionized epidemiological studies of infectious diseases,
including those of a mycobacterial etiology. With the advent of fingerprinting techniques …

In the recent years, a wide range of metabonomic analytical techniques are widely used in
the modern research of traditional Chinese medicine (TCM). At the same time, the …

The validation of quantitative real-time PCR systems and above all, proof of the detection
limit of this method, is a frequently and intensively discussed topic in food pathogen …

MicroRNAs (miRNAs) are a class of approximately 22-nucleotide noncoding RNA molecules
that negatively regulate their target genes in a sequence-specific manner. In the present …

The family of microRNAs (miRNAs) not only plays an important role in gene regulation but is
also useful for the diagnosis of diseases. A reliable method with high sensitivity may allow …

The methylation of the promoter region of DNA is an important regulatory mechanism for the
downstream gene expression, and the extent of methylation has been linked to cancer …

Background Mycobacteria can be quickly and simply identified by PCR restriction-enzyme
analysis (PRA), but misidentification can occur because of similarities in band sizes that are …

Physiological amino acids (AAs) are important indices for monitoring various diseases,
including cancer. This study proposes a polymer-based separation method in the presence …

RNA integrity is important in RNA studies because poor RNA quality may impact
downstream methodologies. This study proposes a rapid and cost-effective method for the …

This article presents a newly developed capillary gel electrophoresis (CGE) using dynamic
coating with hydroxyethylcellulose methodology for the separation of fourteen standard DNA …