Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures,
which can absorb relatively large amounts of fluid. Because of the high water content, soft …

The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

The concept and development of bone/cartilage organoids are rapidly gaining momentum,
providing opportunities for both fundamental and translational research in bone biology …

Tumors can undergo long periods of dormancy, with cancer cells entering a largely
quiescent, nonproliferative state before reactivation and outgrowth. To understand the role of …

Bone organoids, which simulate and construct special organs in vitro with complex
biological functions based on tissue engineering technology, provide dramatically realistic …

Polyethylene glycol (PEG) is a flexible, water-soluble, non-immunogenic, as well as
biocompatible polymer, and it could synergize with polysaccharides for food applications …

Hematopoietic stem cells (HSCs) are fundamental to the generation of the body's blood and
immune cells. They reside primarily within the bone marrow (BM) niche microenvironment …

The human bone marrow (hBM) is a complex organ critical for hematopoietic and immune
homeostasis, and where many cancers metastasize. Understanding the fundamental …

Stiffness is a key property for hydrogels, affecting cellular adhesion, motility, and
differentiation, the integrity of biomedical implants, and the flexibility of wound coverings. A …

Injectable hydrogels are gaining prominence as a biocompatible, minimally invasive, and
adaptable platform for cartilage tissue engineering. Commencing with their synthesis, this …