Biocatalysis has become an important aspect of modern organic synthesis, both in
academia and across the chemical and pharmaceutical industries. Its success has been …

Biocatalysis is a highly valued enabling technology for pharmaceutical research and
development as it can unlock synthetic routes to complex chiral motifs with unparalleled …

Catalytic C–H oxyfunctionalization reactions have garnered significant attention in recent
years with their ability to streamline synthetic routes toward complex molecules …

ATP recycling systems are required to avoid the addition of stoichiometric quantities of
cofactor and facilitate industrial implementation of ATP-dependent enzymes. One factor that …

Enzymes with high activity are readily produced through protein engineering, but
intentionally and efficiently engineering enzymes for an expanded substrate scope is a …

Wood-decaying fungi are the major decomposers of plant litter. Heavy sequencing efforts on
genomes of wood-decaying fungi have recently been made due to the interest in their …

Polyphosphate kinases (PPKs) have emerged as valuable candidates to address the unmet
need for scalable recycling of the common enzyme cofactor adenosine‐5'‐triphosphate …

Enzyme biocatalysis is reshaping pharmaceutical synthesis, offering sustainable and
efficient pathways for drug discovery and production. This paradigm shift towards eco …

GABAA receptor modulators are structurally almost as diverse as their target protein. A
plethora of heterocyclic scaffolds has been described as modulating this extremely important …

Genome mining for novel Fe (II)/α-ketoglutarate-dependent dioxygenases (αKGDs) to
expand the enzymatic repertoire in the oxidation of l-proline is reported. Through clustering …