[HTML][HTML] Mediterranean Diet and Lifestyle in Persons with Mild to Moderate Alzheimer's Disease

LJ Dominguez, N Veronese, A Parisi, F Seminara… - Nutrients, 2024 - pmc.ncbi.nlm.nih.gov
Due to the continuous aging of the population and consequent increase in dementia, focus
on its prevention is of growing importance for public health. Since effective pharmacological …

Management of alcohol withdrawal syndromes in general hospital settings

KA Kast, SA Sidelnik, SH Nejad, J Suzuki - bmj, 2025 - bmj.com
The covid-19 pandemic was associated with an unprecedented increase in alcohol
consumption and associated morbidity, including hospitalizations for alcohol withdrawal …

Alcohol use disorder disrupts BDNF maturation via the PAI-1 pathway which could be reversible with abstinence

S Liu, X Xie, D Zhao, N Jin, Y Hu, W Wang, X Luo… - Scientific Reports, 2024 - nature.com
The plasminogen activator inhibitor-1 (PAI-1)→ mature brain-derived neurotrophic factor
(mBDNF) pathway plays a pivotal role in the conversion of probrain-BDNF (ProBDNF) to …

[HTML][HTML] Serum BDNF and pro-BDNF levels in alcohol use disorders according to depression status: An exploratory study of their evolution two months after withdrawal

T Gellé, T Vinais, A Lacroix, B Plansont, P Nubukpo… - Heliyon, 2024 - cell.com
Abstract Background Alcohol use disorders (AUDs) are complex pathologies with a myriad
of molecular actors involved in both disease progression and remission. Brain-derived …

[HTML][HTML] Protective Effects and Mechanism of Heracleum moellendorffii Hance on Alcohol-Induced Cognitive Decline in Mice

W Park, Y Kim, SH Cho - International Journal of Molecular Sciences, 2024 - mdpi.com
Chronic and continuous alcohol consumption increases the risk of cognitive decline and
may lead to alcohol-related dementia. We investigated the potential of Heracleum …

[HTML][HTML] Design and methodology of the first open-label trial of MDMA-assisted therapy for veterans with post-traumatic stress disorder and alcohol use disorder …

E Eaton, C Capone, BJ Gully, ZE Brown… - Contemporary Clinical …, 2024 - Elsevier
Background Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD)
commonly co-occur and are associated with more severe symptomatology than either …

Genetic determinants of serum brain-derived neurotrophic factor (BDNF) after alcohol withdrawal

D Peregud, A Korolkov, V Baronets, K Kozlov… - Discover …, 2024 - Springer
Peripheral brain-derived neurotrophic factor (BDNF) levels increase during alcohol
abstinence in dependent subjects. Meanwhile, the genetic determinants of circulating BDNF …

Deciphering the Role of Genetics in Alcohol Use Disorder

L Evangelia, K Ilias, M Leonidas, T Elias… - Handbook of the Biology …, 2024 - Springer
This chapter explores the genetic underpinnings of Alcohol Use Disorder (AUD), examining
various aspects from genome-wide association studies (GWAS) to pharmacogenetics. It …

Sex, Drugs, and TBI: The Effects of Sex Hormones and TrkB Activation on Alcohol-Related Behavior Following a Traumatic Brain Injury

RB Oliverio - 2024 - search.proquest.com
Traumatic brain injury (TBI) and alcohol use disorder (AUD) exhibit a bidirectional
relationship: AUD increases the risk of incurring a TBI and, inversely, a history of TBI …

Deciphering the Role of the PAI_1-mBDNF Pathway in Alcohol Use Disorder: Insights into Pathogenesis and Abstinence Treatment Efficacy

S Liu, D Zhao, N Jin, Y Hu, W Wang, X Luo, G Li… - 2024 - researchsquare.com
The pathway of plasminogen activator inhibitor-1 (PAI_1)-brain-derived neurotrophic factor
(BDNF) plays a pivotal role in the conversion of Probrain-derived neurotrophic factor …