Pain in endometriosis

J Maddern, L Grundy, J Castro… - Frontiers in cellular …, 2020 - frontiersin.org
Endometriosis is a chronic and debilitating condition affecting∼ 10% of women.
Endometriosis is characterized by infertility and chronic pelvic pain, yet treatment options …

Pathogenesis of endometriosis: New insights into prospective therapies

R Kapoor, CA Stratopoulou, MM Dolmans - International journal of …, 2021 - mdpi.com
Endometriosis is a female reproductive disorder characterized by growth of uterine cells and
tissue in distant sites. Around 2–10% of women experience this condition during …

An integrated multi-tissue approach for endometriosis candidate biomarkers: a systematic review

A Brulport, M Bourdon, D Vaiman, C Drouet… - Reproductive Biology …, 2024 - Springer
Biomarker identification could help in deciphering endometriosis pathophysiology in
addition to their use in the development of non invasive diagnostic and prognostic …

Neurogenic inflammation in the context of endometriosis—what do we know?

RV Velho, E Taube, J Sehouli, S Mechsner - International Journal of …, 2021 - mdpi.com
Endometriosis (EM) is an estrogen-dependent disease characterized by the presence of
epithelial, stromal, and smooth muscle cells outside the uterine cavity. It is a chronic and …

[HTML][HTML] Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations

LC Giudice, TT Oskotsky, S Falako… - The FASEB …, 2023 - ncbi.nlm.nih.gov
Endometriosis is a common estrogen‐dependent disorder wherein uterine lining tissue
(endometrium) is found mainly in the pelvis where it causes inflammation, chronic pelvic …

New Potential Pharmacological Options for Endometriosis Associated Pain

L García-Izquierdo, P Marín-Sánchez… - International Journal of …, 2024 - mdpi.com
Endometriosis is a chronic inflammatory disorder characterized by the abnormal growth of
endometrial-like tissue outside the uterine cavity, affecting 10–15% of women of …

Distinct subtypes of endometriosis identified based on stromal-immune microenvironment and gene expression: implications for hormone therapy

Y Wang, Y Chen, Y Xiao, J Ruan, Q Tian… - Frontiers in …, 2023 - frontiersin.org
Background Endometriosis (EMs) is a chronic inflammatory condition that is highly
heterogeneous. Current clinical staging fails to accurately predict drug responses and …

Menstrual fluid endometrial stem/progenitor cell and supernatant protein content: cyclical variation and indicative range

KA Wyatt, CE Filby, ML Davies-Tuck… - Human …, 2021 - academic.oup.com
STUDY QUESTION Does natural variation exist in the endometrial stem/progenitor cell and
protein composition of menstrual fluid across menstrual cycles in women? SUMMARY …

A systematic review and meta-analysis on alcohol consumption and risk of endometriosis: an update from 2012

L Li Piani, F Chiaffarino, S Cipriani, P Viganò… - Scientific reports, 2022 - nature.com
Endometriosis is a complex and chronic disease, whose multifactorial nature has
encouraged a deep investigation on the role of lifestyle factors. A strong association …

Higher Oxidative Stress in Endometriotic Lesions Upregulates Senescence-Associated p16ink4a and β-Galactosidase in Stromal Cells

H Malvezzi, BA Cestari, J Meola… - International Journal of …, 2023 - mdpi.com
Endometriosis affects a significant proportion of women worldwide; however, no definitive
cure for this disease has been discovered to date. Oxidative stress promotes endometriotic …