Computation through neural population dynamics

S Vyas, MD Golub, D Sussillo… - Annual review of …, 2020 - annualreviews.org
Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

Principles of corticocortical communication: proposed schemes and design considerations

A Kohn, AI Jasper, JD Semedo, E Gokcen… - Trends in …, 2020 - cell.com
Nearly all brain functions involve routing neural activity among a distributed network of
areas. Understanding this routing requires more than a description of interareal anatomical …

Modeling behaviorally relevant neural dynamics enabled by preferential subspace identification

OG Sani, H Abbaspourazad, YT Wong, B Pesaran… - Nature …, 2021 - nature.com
Neural activity exhibits complex dynamics related to various brain functions, internal states
and behaviors. Understanding how neural dynamics explain specific measured behaviors …

The centrality of population-level factors to network computation is demonstrated by a versatile approach for training spiking networks

B DePasquale, D Sussillo, LF Abbott, MM Churchland - Neuron, 2023 - cell.com
Neural activity is often described in terms of population-level factors extracted from the
responses of many neurons. Factors provide a lower-dimensional description with the aim of …

Phantom oscillations in principal component analysis

M Shinn - Proceedings of the National Academy of …, 2023 - National Acad Sciences
Principal component analysis (PCA) is a dimensionality reduction method that is known for
being simple and easy to interpret. Principal components are often interpreted as low …

Feedforward and feedback interactions between visual cortical areas use different population activity patterns

JD Semedo, AI Jasper, A Zandvakili, A Krishna… - Nature …, 2022 - nature.com
Brain function relies on the coordination of activity across multiple, recurrently connected
brain areas. For instance, sensory information encoded in early sensory areas is relayed to …

[HTML][HTML] Hand knob area of premotor cortex represents the whole body in a compositional way

FR Willett, DR Deo, DT Avansino, P Rezaii… - Cell, 2020 - cell.com
Decades after the motor homunculus was first proposed, it is still unknown how different
body parts are intermixed and interrelated in human motor cortical areas at single-neuron …

The science and engineering behind sensitized brain-controlled bionic hands

C Pandarinath, SJ Bensmaia - Physiological Reviews, 2022 - journals.physiology.org
Advances in our understanding of brain function, along with the development of neural
interfaces that allow for the monitoring and activation of neurons, have paved the way for …

Organizing recurrent network dynamics by task-computation to enable continual learning

L Duncker, L Driscoll, KV Shenoy… - Advances in neural …, 2020 - proceedings.neurips.cc
Biological systems face dynamic environments that require continual learning. It is not well
understood how these systems balance the tension between flexibility for learning and …

Brain control of bimanual movement enabled by recurrent neural networks

DR Deo, FR Willett, DT Avansino, LR Hochberg… - Scientific Reports, 2024 - nature.com
Brain-computer interfaces have so far focused largely on enabling the control of a single
effector, for example a single computer cursor or robotic arm. Restoring multi-effector motion …