Corneal stromal repair and regeneration

RR Mohan, D Kempuraj, S D'Souza, A Ghosh - Progress in retinal and eye …, 2022 - Elsevier
The cornea is a specialized, transparent, avascular, immune-privileged, and heavily
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …

Anatomy of cornea and ocular surface

MS Sridhar - Indian journal of ophthalmology, 2018 - journals.lww.com
Important functions of cornea in the eye include protecting the structures inside the eye,
contributing to the refractive power of the eye, and focusing light rays on the retina with …

Poly(l‐Histidine)‐Mediated On‐Demand Therapeutic Delivery of Roughened Ceria Nanocages for Treatment of Chemical Eye Injury

CJ Yang, DD Nguyen, JY Lai - Advanced Science, 2023 - Wiley Online Library
Abstract Development of topical bioactive formulations capable of overcoming the low
bioavailability of conventional eye drops is critically important for efficient management of …

Print me an organ! Why we are not there yet

WL Ng, CK Chua, YF Shen - Progress in Polymer Science, 2019 - Elsevier
Bioprinting offers a highly-automated and advanced manufacturing platform that facilitates
the deposition of bio-inks (living cells, biomaterials and growth factors) in a scalable and …

[HTML][HTML] 3D bioprinting of a corneal stroma equivalent

A Isaacson, S Swioklo, CJ Connon - Experimental eye research, 2018 - Elsevier
Corneal transplantation constitutes one of the leading treatments for severe cases of loss of
corneal function. Due to its limitations, a concerted effort has been made by tissue engineers …

Composition, structure and function of the corneal stroma

EM Espana, DE Birk - Experimental eye research, 2020 - Elsevier
No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …

[HTML][HTML] Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks

A Sorkio, L Koch, L Koivusalo, A Deiwick, S Miettinen… - Biomaterials, 2018 - Elsevier
There is a high demand for developing methods to produce more native-like 3D corneal
structures. In the present study, we produced 3D cornea-mimicking tissues using human …

Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery

A Than, C Liu, H Chang, PK Duong… - Nature …, 2018 - nature.com
Eye diseases and injuries impose a significant clinical problem worldwide. Safe and
effective ocular drug delivery is, however, challenging due to the presence of ocular barriers …

Myofibroblast transdifferentiation: The dark force in ocular wound healing and fibrosis

DY Shu, FJ Lovicu - Progress in retinal and eye research, 2017 - Elsevier
Wound healing is one of the most complex biological processes to occur in life. Repair of
tissue following injury involves dynamic interactions between multiple cell types, growth …

Corneal nerves in health and disease

MA Al-Aqaba, VK Dhillon, I Mohammed… - Progress in retinal and …, 2019 - Elsevier
The cornea is the most sensitive structure in the human body. Corneal nerves adapt to
maintain transparency and contribute to corneal health by mediating tear secretion and …