[PDF][PDF] Cancer statistics, 2024.

RL Siegel, AN Giaquinto, A Jemal - CA: a cancer journal for …, 2024 - pinchnews.com
Abstract Each year, the American Cancer Society estimates the numbers of new cancer
cases and deaths in the United States and compiles the most recent data on population …

Translating biological insights into improved management of endometrial cancer

JA How, AA Jazaeri, SN Westin, BC Lawson… - Nature Reviews …, 2024 - nature.com
Endometrial cancer (EC) is the most common gynaecological cancer among women in high-
income countries, with both incidence and mortality continuing to increase. The complexity …

[HTML][HTML] PD-1/PD-L1 inhibitors plus carboplatin and paclitaxel compared with carboplatin and paclitaxel in primary advanced or recurrent endometrial cancer: a …

FCA de Moraes, E Pasqualotto, LM Lopes… - BMC cancer, 2023 - Springer
Background Paclitaxel and carboplatin is the standard chemotherapy for the treatment of
advanced or recurrent endometrial cancer. However, the benefit of adding programmed cell …

Atezolizumab and chemotherapy for advanced or recurrent endometrial cancer (AtTEnd): a randomised, double-blind, placebo-controlled, phase 3 trial

N Colombo, E Biagioli, K Harano, F Galli… - The Lancet …, 2024 - thelancet.com
Background At the time of AtTEnd trial design, standard treatment for advanced or recurrent
endometrial cancer included carboplatin and paclitaxel chemotherapy. This trial assessed …

Prognostic impact and causality of age on oncological outcomes in women with endometrial cancer: a multimethod analysis of the randomised PORTEC-1, PORTEC-2 …

FC Wakkerman, J Wu, H Putter… - The Lancet …, 2024 - thelancet.com
Background Numerous studies have shown that older women with endometrial cancer have
a higher risk of recurrence and cancer-related death. However, it remains unclear whether …

MITO END-3: efficacy of avelumab immunotherapy according to molecular profiling in first-line endometrial cancer therapy

S Pignata, D Califano, D Lorusso, L Arenare… - Annals of …, 2024 - Elsevier
Background Immunotherapy combined with chemotherapy significantly improves
progression-free survival (PFS) compared to first-line chemotherapy alone in advanced …

Immune Checkpoint Inhibitors and Cardiotoxicity: A Comparative Meta‐Analysis of Observational Studies and Randomized Controlled Trials

A Sharma, G Alexander, JH Chu… - Journal of the …, 2024 - Am Heart Assoc
Background Immune checkpoint inhibitors (ICIs) have uncommon associations with
cardiotoxicity, yet these cardiotoxic effects are associated with high mortality. An accurate …

Incorporation of anti-PD1 or anti PD-L1 agents to platinum-based chemotherapy for the primary treatment of advanced or recurrent endometrial cancer. A meta …

M Bartoletti, M Montico, D Lorusso, R Mazzeo… - Cancer Treatment …, 2024 - Elsevier
Importance Various randomized trials have explored the efficacy of combining immune
checkpoint inhibitors (ICIs) with first-line chemotherapy in advanced endometrial cancer. We …

[HTML][HTML] Efficacy and safety of immune checkpoint inhibitors for advanced or recurrent endometrial cancer: a systematic review and network meta-analysis

D Huang, S Li, Y Bai, Y Wang - BMC cancer, 2024 - Springer
Background Currently, several randomized controlled trials (RCTs) have been conducted to
investigate the efficacy of combining immune checkpoint inhibitors (ICIs) with chemotherapy …

[HTML][HTML] Major clinical research advances in gynecologic cancer in 2023: a tumultuous year for endometrial cancer

SH Shim, JY Lee, YY Lee, JY Park, YJ Lee… - Journal of …, 2024 - ncbi.nlm.nih.gov
In the 2023 series, we summarized the major clinical research advances in gynecologic
oncology based on communications at the conference of Asian Society of Gynecologic …