The condensation of 5-aminopyrazole with various bielectrophilic moieties results in the
formation of pyrazoloazines, an interesting array of fused heterocyclic systems. The …

Abstract Pyrazolo [3, 4-d] pyrimidine ring system constitute an important class of heterocyclic
compounds which can serve as a promising scaffold exhibiting many pharmacological …

Abstract The pyrazolo [3, 4‐d] pyrimidine core has received a lot of interest from the
medicinal chemistry community as a promising framework for drug design and discovery. It …

A highly efficient method for the synthesis of azole derivatives via a direct aza-Michael
addition of azoles to α, β-unsaturated malonates using Cs2CO3 as a catalyst, has been …

Abstract The imidazo [1, 2-a] pyrazine ring system has been chosen as a new decorable
core skeleton for the design of novel adenosine receptor (AR) antagonists targeting either …

Adenosine was defined as a neuromodulator which exerts its action by interaction with
specific G-protein coupled receptor termed adenosine receptors. Adenosine receptors are …

ABSTRACT A series of pyrazolo [3, 4-d] pyrimidine-4-one derivatives was conveniently
synthesized via tandem aza-Wittig and annulation reactions of the corresponding …

An environmentally benign, simple, and efficient procedure has been developed for the one-
pot multicomponent synthesis of pyrazolo [3, 4-d] pyrimidine-6-one derivatives by the …

The condensation of 5-aminopyrazole with various bielectrophilic moieties results in the
formation of pyrazoloazines, an interesting array of fused heterocyclic systems. The …