HIV entry and envelope glycoprotein-mediated fusion

R Blumenthal, S Durell, M Viard - Journal of Biological Chemistry, 2012 - ASBMB
HIV entry involves binding of the trimeric viral envelope glycoprotein (Env) gp120/gp41 to
cell surface receptors, which triggers conformational changes in Env that drive the …

Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides

R Chan, PD Uchil, J Jin, G Shui, DE Ott… - Journal of …, 2008 - Am Soc Microbiol
Retroviruses acquire a lipid envelope during budding from the membrane of their hosts.
Therefore, the composition of this envelope can provide important information about the …

Kinetics of receptor-mediated endocytosis of elastic nanoparticles

X Yi, H Gao - Nanoscale, 2017 - pubs.rsc.org
It is now widely recognized that mechanical properties play critical roles in the cell uptake of
nanomaterials. Here we conduct a theoretical study on the kinetics of receptor-mediated …

[HTML][HTML] The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases

EL Smith, EH Schuchman - The FASEB journal, 2008 - ncbi.nlm.nih.gov
Abstract Acid sphingomyelinase (ASM; EC 3.1. 4.12) is best known for its involvement in the
lysosomal storage disorder Niemann-Pick disease (NPD). Through studies that began by …

[HTML][HTML] Fluorescence correlation spectroscopy in membrane structure elucidation

S Chiantia, J Ries, P Schwille - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
This review describes the application of fluorescence correlation spectroscopy (FCS) for the
study of biological membranes. Monitoring the fluorescence signal fluctuations, it is possible …

The manifold roles of sphingolipids in viral infections

E Avota, J Bodem, J Chithelen, P Mandasari… - Frontiers in …, 2021 - frontiersin.org
Sphingolipids are essential components of eukaryotic cells. In this review, we want to
exemplarily illustrate what is known about the interactions of sphingolipids with various …

Sphingolipids in viral infection

J Schneider-Schaulies… - Biological chemistry, 2015 - degruyter.com
Viruses exploit membranes and their components such as sphingolipids in all steps of their
life cycle including attachment and membrane fusion, intracellular transport, replication …

Lipids in pathophysiology and development of the membrane lipid therapy: new bioactive lipids

M Torres, S Parets, J Fernández-Díaz, R Beteta-Göbel… - Membranes, 2021 - mdpi.com
Membranes are mainly composed of a lipid bilayer and proteins, constituting a checkpoint
for the entry and passage of signals and other molecules. Their composition can be …

Involvement of ceramide in the propagation of Japanese encephalitis virus

H Tani, M Shiokawa, Y Kaname, H Kambara… - Journal of …, 2010 - Am Soc Microbiol
Japanese encephalitis virus (JEV) is a mosquito-borne RNA virus and one of the most
important flaviviruses in the medical and veterinary fields. Although cholesterol has been …

The role of lipids in retrovirus replication

AA Waheed, EO Freed - Viruses, 2010 - mdpi.com
Retroviruses undergo several critical steps to complete a replication cycle. These include
the complex processes of virus entry, assembly, and budding that often take place at the …