The principles, design and applications of fused-ring electron acceptors

J Wang, P Xue, Y Jiang, Y Huo, X Zhan - Nature Reviews Chemistry, 2022 - nature.com
Fused-ring electron acceptors (FREAs) have a donor–acceptor–donor structure comprising
an electron-donating fused-ring core, electron-accepting end groups, π-bridges and side …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Acceptor Planarization and Donor Rotation: A Facile Strategy for Realizing Synergistic Cancer Phototherapy via Type I PDT and PTT

L Feng, C Li, L Liu, Z Wang, Z Chen, J Yu, W Ji… - ACS …, 2022 - ACS Publications
Tumor hypoxia seriously impairs the therapeutic outcomes of type II photodynamic therapy
(PDT), which is highly dependent upon tissue oxygen concentration. Herein, a facile strategy …

BODIPY‐based photodynamic agents for exclusively generating superoxide radical over singlet oxygen

KX Teng, WK Chen, LY Niu, WH Fang… - Angewandte Chemie …, 2021 - Wiley Online Library
Developing Type‐I photosensitizers is considered as an efficient approach to overcome the
deficiency of traditional photodynamic therapy (PDT) for hypoxic tumors. However, it remains …

Coupling probiotics with 2D CoCuMo‐LDH nanosheets as a tumor‐microenvironment‐responsive platform for precise NIR‐II photodynamic therapy

Y Yang, T Hu, Y Bian, F Meng, S Yu, H Li… - Advanced …, 2023 - Wiley Online Library
Photodynamic therapy (PDT) has become a promising cancer treatment approach with
superior advantages. However, it remains a grand challenge to develop tumor …

Achieving efficient NIR‐II type‐I photosensitizers for photodynamic/photothermal therapy upon regulating chalcogen elements

K Wen, H Tan, Q Peng, H Chen, H Ma… - Advanced …, 2022 - Wiley Online Library
Second near‐infrared (NIR‐II) window type‐I photosensitizers have intrinsic advantages in
photodynamic/photothermal therapy (PDT/PTT) of some malignant tumors with deep …

Fluorination enhances NIR‐II emission and photothermal conversion efficiency of phototheranostic agents for imaging‐guided cancer therapy

C Li, G Jiang, J Yu, W Ji, L Liu, P Zhang… - Advanced …, 2023 - Wiley Online Library
Phototheranostics with second near‐infrared (NIR‐II) imaging and photothermal effect have
become a burgeoning biotechnology for tumor diagnosis and precise treatment. As …

Cationization-enhanced type I and type II ROS generation for photodynamic treatment of drug-resistant bacteria

S Liu, B Wang, Y Yu, Y Liu, Z Zhuang, Z Zhao, G Feng… - ACS …, 2022 - ACS Publications
Photodynamic therapy as an emerging phototheranostic approach holds great potential for
antibacterial treatment, but is limited by compromised reactive oxygen species (ROS) …

Efficient NIR-II type-I AIE photosensitizer for mitochondria-targeted photodynamic therapy through synergistic apoptosis–ferroptosis

J Zhuang, B Wang, H Chen, K Zhang, N Li, N Zhao… - ACS …, 2023 - ACS Publications
Hypoxia, the hallmark of malignant tumors, has been recognized as a major obstacle for
photodynamic therapy (PDT). Precisely targeting cancer cells in intricate biological …

A supramolecular photosensitizer derived from an Arene-Ru (II) complex self-assembly for NIR activated photodynamic and photothermal therapy

G Xu, C Li, C Chi, L Wu, Y Sun, J Zhao, XH Xia… - Nature …, 2022 - nature.com
Effective photosensitizers are of particular importance for the widespread clinical utilization
of phototherapy. However, conventional photosensitizers are usually plagued by short …