Causing approximately 10 million incident cases and 1.3–1.5 million deaths every year,
Mycobacterium tuberculosis remains a global health problem. The risk is further …

Parkinson's disease (PD) is the second most common neurodegenerative disease. In recent
years, it has been shown that leucine-rich repeat kinase 2 (LRRK2) has a crucial function in …

It is critical that novel classes of antituberculosis drugs are developed to combat the
increasing burden of infections by multidrug-resistant strains. To identify such a novel class …

Flavoprotein oxidoreductases are members of a large protein family of specialized
dehydrogenases, which include type II NADH dehydrogenase, pyridine nucleotide …

Fragment based drug design (FBDD) is a structure guided ligand design approach used in
the process of drug discovery. It involves identification of low molecular weight fragments as …

Mycobacterium tuberculosis remains a leading cause of infectious disease morbidity and
mortality for which new drug combination therapies are needed. Mycobacterial …

The increasing prevalence of drug resistant tuberculosis has created an urgent need for new
antibiotics with novel modes of action. New drug targets include various enzymes in the …

Tuberculosis (TB) remains a global health problem and the emergence of HIV has further
worsened it. Long chemotherapy and the emergence of drug-resistance strains of …

Drug‐resistant strains of Mycobacterium tuberculosis are on the rise and have resulted in an
urgent need to develop new tuberculosis (TB) drugs. Herein, the development of chromonyl …

A large number of natural products, especially those used in ethnomedicine of malaria, have
shown varying in vitro antiplasmodial activities. Facilitating antimalarial drug development …