Chalcone scaffolds, bioprecursors of flavonoids: Chemistry, bioactivities, and pharmacokinetics

M Rudrapal, J Khan, AAB Dukhyil, RMII Alarousy… - Molecules, 2021 - mdpi.com
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …

Stilbenes, a versatile class of natural metabolites for inflammation—an overview

JM Al-Khayri, R Mascarenhas, HM Harish, Y Gowda… - Molecules, 2023 - mdpi.com
Stilbenes are polyphenolic allelochemicals synthesized by plants, especially grapes,
peanuts, rhubarb, berries, etc., to defend themselves under stressful conditions. They are …

Hydroxy chalcones and analogs with chemopreventive properties

ML Birsa, LG Sarbu - International Journal of Molecular Sciences, 2023 - mdpi.com
The aim of this review is to highlight the chemopreventive properties of hydroxy-substituted
natural and synthetic chalcones along with a number of their analogs. These products …

Cytotoxic steroidal glycosides from the rhizomes of Paris polyphylla var. yunnanensis

Y Liu, MY Liu, LL Bi, YY Tian, PC Qiu, XY Qian… - Phytochemistry, 2023 - Elsevier
Paris polyphylla var. yunnanensis (Franch.) Hand.-Mazz.(Melanthiaceae), an important
specie of the genus Paris, has long been in a traditional Chinese medicine (TCM) for a long …

Stereochemical investigations of bioactive dihydrobenzofuran-type lignanamides from Solanum lyratum: chiral resolution, in vitro and in silico profiling

Y Chang, ZK Duan, X Zhang, JY Hou, JQ Niu… - New Journal of …, 2023 - pubs.rsc.org
Six pairs of enantiomeric dihydrobenzofuran-type lignanamides consisting of nine
undescribed compounds (1a, 2a/2b–3a, and 4b–6a/6b), along with a previously …

Stereochemical insights into structurally diverse lignanamides from the herbs of Solanum lyratum Thunb.

Y Chang, M Bai, X Zhang, JY Hou, CY Chu, JQ Niu… - Phytochemistry, 2023 - Elsevier
A chemical investigation of Solanum lyratum Thunb.(Solanaceae) afforded six pairs of
enantiomeric lignanamides consisting of twelve undescribed compounds, along with two …

Steroidal saponins with cytotoxic effects from the rhizomes of Asparagus cochinchinensis

B Liu, B Li, D Zhou, X Wen, Y Wang, G Chen, N Li - Bioorganic Chemistry, 2021 - Elsevier
In the ongoing research on potent antitumor agents from the rhizomes of Asparagus
cochinchinensis, seven undescribed steroidal saponins asparagusoside A–G (1–7), along …

Glucose-Triggered Release of trans-N-p-Coumaroyltyramine from Zeolitic Imidazolate Framework-8 (ZIF8) Modified with Dioscorea opposita Thunb Polysaccharide

W Liu, X Wang, X Fan, D Zhou, W Hu, X Liu, J Zhu - Langmuir, 2023 - ACS Publications
A Dioscorea opposita Thunb polysaccharide (DOP)-modified ZIF8 material was developed
in this study, which can be used as a “smart” glucose-responsive carrier to control the slow …

Cytotoxic alkaloids from the root of Zanthoxylum paracanthum (mildbr) Kokwaro

LK Omosa, VA Nchiozem-Ngnitedem… - Natural Product …, 2022 - Taylor & Francis
Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide
derivative,(2 E, 4 E)-6-oxo-N-isobutyldeca-2, 4-dienamide (1) together with 10 known …

Four Pairs of Neuroprotective Aryldihydronaphthalene‐Type Lignanamide Enantiomers from the Herbs of Solanum lyratum

SH Mi, Y Chang, X Zhang, JY Hou, JQ Niu… - Chemistry & …, 2023 - Wiley Online Library
Four pairs of aryldihydronaphthalene‐type lignanamide enantiomers were isolated from
Solanum lyratum (Solanaceae). The enantiomeric separation was accomplished by chiral …