An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus
The hippocampus contains many unique cell types, which serve the structure's specialized
functions, including learning, memory and cognition. These cells have distinct spatial …
functions, including learning, memory and cognition. These cells have distinct spatial …
Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume
Y Uchimura, K Hino, K Hattori, Y Kubo, A Owada… - Plos one, 2024 - journals.plos.org
Epidemiological studies suggest that poor nutrition during pregnancy predisposes offspring
to the development of lifestyle-related noncommunicable diseases and psychiatric disorders …
to the development of lifestyle-related noncommunicable diseases and psychiatric disorders …
[HTML][HTML] Formation and Retrieval of Cell Assemblies in a Biologically Realistic Spiking Neural Network Model of Area CA3 in the Mouse Hippocampus
The hippocampal formation is critical for episodic memory, with area Cornu Ammonis 3
(CA3) a necessary substrate for auto-associative pattern completion. Recent theoretical and …
(CA3) a necessary substrate for auto-associative pattern completion. Recent theoretical and …
A Continuous Attractor Model with Realistic Neural and Synaptic Properties Quantitatively Reproduces Grid Cell Physiology
NM Sutton, BE Gutiérrez-Guzmán… - International Journal of …, 2024 - mdpi.com
Computational simulations with data-driven physiological detail can foster a deeper
understanding of the neural mechanisms involved in cognition. Here, we utilize the wealth of …
understanding of the neural mechanisms involved in cognition. Here, we utilize the wealth of …
Building a mathematical model of the brain
F Skinner - Elife, 2024 - elifesciences.org
Computational Neuroscience: Building a mathematical model of the brain | eLife Skip to Content
eLife logo eLife home page Menu Home Magazine Community About Search Alerts Submit …
eLife logo eLife home page Menu Home Magazine Community About Search Alerts Submit …
Biophysical modulation and robustness of itinerant complexity in neuronal networks
S Venkadesh, A Shaikh, H Shakeri… - Frontiers in Network …, 2024 - frontiersin.org
Transient synchronization of bursting activity in neuronal networks, which occurs in patterns
of metastable itinerant phase relationships between neurons, is a notable feature of network …
of metastable itinerant phase relationships between neurons, is a notable feature of network …
Biologically-Informed Excitatory and Inhibitory Balance for Robust Spiking Neural Network Training
Spiking neural networks drawing inspiration from biological constraints of the brain promise
an energy-efficient paradigm for artificial intelligence. However, challenges exist in …
an energy-efficient paradigm for artificial intelligence. However, challenges exist in …
Gather your neurons and model together: Community times ahead
M Diamantaki, A Papoutsi - PLoS biology, 2024 - journals.plos.org
Bottom-up, data-driven, large-scale models provide a mechanistic understanding of
neuronal functions. A new study in PLOS Biology builds a biologically realistic model of the …
neuronal functions. A new study in PLOS Biology builds a biologically realistic model of the …
Improving the adaptive and continuous learning capabilities of artificial neural networks: Lessons from multi-neuromodulatory dynamics
J Mei, A Rodriguez-Garcia, D Takeuchi… - arXiv preprint arXiv …, 2025 - arxiv.org
Continuous, adaptive learning-the ability to adapt to the environment and improve
performance-is a hallmark of both natural and artificial intelligence. Biological organisms …
performance-is a hallmark of both natural and artificial intelligence. Biological organisms …
Synaptic proteome diversity is primarily driven by gene regulation of glutamate receptors and their regulatory proteins
R Reig-Viader, D del Castillo-Berges, A Burgas-Pau… - bioRxiv, 2024 - biorxiv.org
Electrophysiological features of excitatory synapses vary widely throughout the brain,
granting neuronal circuits the ability to decode and store diverse patterns of information …
granting neuronal circuits the ability to decode and store diverse patterns of information …