The Bactericidal Tandem Drug, AB569: How to Eradicate Antibiotic-Resistant Biofilm Pseudomonas aeruginosa in Multiple Disease Settings Including Cystic Fibrosis …

DJ Hassett, RA Kovall, MJ Schurr, N Kotagiri… - Frontiers in …, 2021 - frontiersin.org
The life-threatening pandemic concerning multi-drug resistant (MDR) bacteria is an evolving
problem involving increased hospitalizations, billions of dollars in medical costs and a …

AB569, a novel, topical bactericidal gel formulation, kills Pseudomonas aeruginosa and promotes wound healing in a murine model of burn wound infection

A Barry, W Panmanee, DJ Hassett… - Infection and …, 2021 - Am Soc Microbiol
Cutaneous thermal injuries from burns/explosives are a major cause of morbidity and
mortality and represent a monumental burden on our current health care system. Injury …

AB569, a non-toxic combination of acidified nitrite and EDTA, is effective at killing the notorious Iraq/Afghanistan combat wound pathogens, multi-drug resistant …

AL Bogue, W Panmanee, CT McDaniel, JE Mortensen… - Plos one, 2021 - journals.plos.org
Multi-drug resistant (MDR) Acinetobacter baumannii (Ab) and Acinetobacter spp. present
monumental global health challenges. These organisms represent model Gram-negative …

Nitric Oxide-Mediated Dispersal as an Adjunctive Strategy for the Control of Biofilm-Associated Infection

D Power, J Webb - Antibiofilm Strategies: Current and Future Applications …, 2022 - Springer
Structured biofilm aggregates offer an increased tolerance to antimicrobials, providing either
a physical barrier to antimicrobial penetration or leading to physiological adaptations …

A novel bactericidal drug effective against Gram-positive and Gram-negative pathogenic bacteria: easy as AB569

DJ Hassett, TJ Meyer - DNA and Cell Biology, 2020 - liebertpub.com
Global antibiotic resistance, driven by intensive antibiotic exposure/abuse, constitutes a
serious challenge to all health care, particularly in an era when new antimicrobial …

Analysis of urine samples for antimicrobial resistance profiles in Grenada, 2015-2018

MJ Montalbano, MD Shawn Charles… - International Public …, 2020 - search.proquest.com
Antimicrobial resistance (AMR) is a serious global public health problem. There is a
worldwide mortality of half-a-million people per year from AMR infections and additional …