Background Direct oral anticoagulants (DOACs) are the treatment of choice for most patients
with atrial fibrillation and/or noncancer-associated venous thromboembolic disease …

Non–vitamin K oral anticoagulants (NOACs) are now widely used as alternatives to warfarin
for stroke prevention in atrial fibrillation and management of venous thromboembolism. In …

Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

This guidance document was prepared on behalf of the International Council for
Standardization in Haematology (ICSH) for providing haemostasis-related guidance …

Viscoelastic-based techniques to evaluate whole blood hemostasis have advanced
substantially since they were first developed over 70 years ago but are still based upon the …

Trauma-induced coagulopathy is associated with very high mortality, and hemorrhage
remains the leading preventable cause of death after injury. Directed methods to combat …

Objectives To provide an overview of the clot viscoelastic testing technology and to describe
its utility in guiding blood product transfusions. Methods A case scenario will be discussed …

Direct oral anticoagulants (DOACs) offer noninferior efficacy and improved safety compared
to vitamin K antagonists (VKAs) for the prevention and treatment of venous …

Background In case of bleeding patients and in acute care, the assessment of residual direct
oral anticoagulant (DOAC) activity is essential for evaluating the potential impact on …

This review provides a comprehensive and up-to-date overview of point-of-care (POC)
devices most commonly used for coagulation analyses in the acute settings. Fast and …