Radiotherapy (RT) is a cancer treatment that uses high doses of radiation to kill cancer cells
and shrink tumors. Although great success has been achieved on radiotherapy, there is still …

Cytokines are a class of potent immunoregulatory proteins that are secreted in response to
various stimuli and act locally to regulate many aspects of human physiology and disease …

As one of the four major means of cancer treatment including surgery, radiotherapy (RT),
chemotherapy, immunotherapy, RT can be applied to various cancers as both a radical …

Sarcomas are uncommon malignancies of mesenchymal origin that can arise throughout the
human lifespan, at any part of the body. Surgery remains the optimal treatment modality …

Simple Summary Oxygen-guided radiotherapy is a new modality for cancer irradiation.
Spatially Fractionated Radiation Therapy allows the treatment of hypoxic tumor areas with …

Background Current clinical trials are using radiation therapy (RT) to enhance an antitumor
response elicited by high-dose interleukin (IL)-2 therapy or immune checkpoint blockade …

Abstract Background Combining interleukin-2 (IL-2) with radiotherapy (RT) and immune
checkpoint blockade (ICB) has emerged as a promising approach to address ICB …

Background Tumor cell death caused by radiation therapy (RT) triggers antitumor immunity
in part because dying cells release adjuvant factors that amplify and sustain dendritic cell …

Background Tumor endothelial marker 1 (TEM1) is a protein expressed in the tumor-
associated endothelium and/or stroma of various types of cancer. We previously …

Immune checkpoint inhibitors (ICIs) have brought new hope for the treatment of patients with
small cell lung cancer (SCLC) over the past decades. However, the overall response rate is …