Blockchain distributed ledger technologies for biomedical and health care applications

TT Kuo, HE Kim, L Ohno-Machado - Journal of the American …, 2017 - academic.oup.com
Objectives To introduce blockchain technologies, including their benefits, pitfalls, and the
latest applications, to the biomedical and health care domains. Target Audience Biomedical …

[HTML][HTML] Clinical information extraction applications: a literature review

Y Wang, L Wang, M Rastegar-Mojarad, S Moon… - Journal of biomedical …, 2018 - Elsevier
Background With the rapid adoption of electronic health records (EHRs), it is desirable to
harvest information and knowledge from EHRs to support automated systems at the point of …

Big data analytics in healthcare

A Belle, R Thiagarajan… - BioMed research …, 2015 - Wiley Online Library
The rapidly expanding field of big data analytics has started to play a pivotal role in the
evolution of healthcare practices and research. It has provided tools to accumulate, manage …

Modelchain: Decentralized privacy-preserving healthcare predictive modeling framework on private blockchain networks

TT Kuo, L Ohno-Machado - arXiv preprint arXiv:1802.01746, 2018 - arxiv.org
Cross-institutional healthcare predictive modeling can accelerate research and facilitate
quality improvement initiatives, and thus is important for national healthcare delivery …

[HTML][HTML] The potential of blockchain technology for health information exchange: experimental study from patients' perspectives

P Esmaeilzadeh, T Mirzaei - Journal of medical Internet research, 2019 - jmir.org
Background Nowadays, a number of mechanisms and tools are being used by health care
organizations and physicians to electronically exchange the personal health information of …

“Big data” and the electronic health record

MK Ross, W Wei… - Yearbook of medical …, 2014 - thieme-connect.com
Objectives: Implementation of Electronic Health Record (EHR) systems continues to expand.
The massive number of patient encounters results in high amounts of stored data …

Functional genomics data: privacy risk assessment and technological mitigation

G Gürsoy, T Li, S Liu, E Ni, CM Brannon… - Nature Reviews …, 2022 - nature.com
The generation of functional genomics data by next-generation sequencing has increased
greatly in the past decade. Broad sharing of these data is essential for research …

HEALER: homomorphic computation of ExAct Logistic rEgRession for secure rare disease variants analysis in GWAS

S Wang, Y Zhang, W Dai, K Lauter, M Kim… - …, 2016 - academic.oup.com
Motivation: Genome-wide association studies (GWAS) have been widely used in
discovering the association between genotypes and phenotypes. Human genome data …

G rid Binary LO gistic RE gression (GLORE): building shared models without sharing data

Y Wu, X Jiang, J Kim… - Journal of the American …, 2012 - academic.oup.com
Objective The classification of complex or rare patterns in clinical and genomic data requires
the availability of a large, labeled patient set. While methods that operate on large …

WebDISCO: a web service for distributed cox model learning without patient-level data sharing

CL Lu, S Wang, Z Ji, Y Wu, L Xiong… - Journal of the …, 2015 - academic.oup.com
Abstract Objective The Cox proportional hazards model is a widely used method for
analyzing survival data. To achieve sufficient statistical power in a survival analysis, it …