Anal cancer is a rare disease that accounts for< 1% and< 3% of all new cancer diagnoses
and gastrointestinal tumours, respectively. The most common histological subtype is …

Chemoradiotherapy is the primary treatment for patients with squamous cell carcinoma of
the anus, but variations in the reported outcomes have restricted between-study …

Introduction: There is a paucity of data on incidence and mechanisms of long-term
gastrointestinal consequences after chemoradiotherapy for anal cancer. Most of the adverse …

Background Locally advanced or metastatic squamous carcinoma of the anal canal (SCAC)
has poor prognosis following platinum-based chemotherapy. Retifanlimab (INCMGA00012) …

Human cancer is a multifaceted decease. Throughout the years several techniques and
technologies have been proposed for the diagnosis and treatment of such deceases …

Purpose Anal cancer is a mainly treated with chemoradiotherapy. A small number of patients
undergo salvage surgery. There are few published studies investigating quality of life and …

Background Concurrent chemoradiotherapy is the standard treatment for anal cancer.
Following national UK implementation of intensity-modulated radiotherapy (IMRT), this …

Purpose To conduct a systematic review evaluating the impact of high dose rate (HDR)
brachytherapy (BT) on the clinical outcomes and toxicities of patients with anal cancer …

Abstract Aim Six Phase III randomized trials have determined the effectiveness of
chemoradiotherapy as primary treatment for anal squamous cell carcinoma (ASCC), but …

BACKGROUND: Local recurrence is a significant risk after anal squamous cell carcinoma.
OBJECTIVES: This study aimed to examine the occurrence of high-grade squamous …