[HTML][HTML] Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke

M Hikichi, K Mizumura, S Maruoka… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) is a common respiratory disease that is
characterized by functional and structural alterations primarily caused by long-term …

The cytokine network in asthma and chronic obstructive pulmonary disease

PJ Barnes - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
Asthma and chronic obstructive pulmonary disease (COPD) are very common inflammatory
diseases of the airways. They both cause airway narrowing and are increasing in incidence …

A meta-analysis of comorbidities in COVID-19: Which diseases increase the susceptibility of SARS-CoV-2 infection?

MK Singh, A Mobeen, A Chandra, S Joshi… - Computers in biology …, 2021 - Elsevier
Comorbidities in COVID-19 patients often lead to more severe outcomes. The disease-
specific molecular events, which may induce susceptibility to Severe Acute Respiratory …

The cytokine network in chronic obstructive pulmonary disease

PJ Barnes - American journal of respiratory cell and molecular …, 2009 - atsjournals.org
Multiple cytokines play a role in the orchestration of inflammation in inflammatory airway
diseases, such as chronic obstructive pulmonary disease, through the recruitment, activation …

Tissue-specific role of CX3CR1 expressing immune cells and their relationships with human disease

M Lee, Y Lee, J Song, J Lee, SY Chang - Immune network, 2018 - synapse.koreamed.org
Abstract Chemokine (C-X3-C motif) ligand 1 (CX 3 CL1, also known as fractalkine) and its
receptor chemokine (C-X3-C motif) receptor 1 (CX 3 CR1) are widely expressed in immune …

Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice

SM Cloonan, K Glass, ME Laucho-Contreras… - Nature medicine, 2016 - nature.com
Chronic obstructive pulmonary disease (COPD) is linked to both cigarette smoking and
genetic determinants. We have previously identified iron-responsive element–binding …

Gene expression networks in COPD: microRNA and mRNA regulation

ME Ezzie, M Crawford, JH Cho, R Orellana, S Zhang… - Thorax, 2012 - thorax.bmj.com
Background The mechanisms underlying chronic obstructive pulmonary disease (COPD)
remain unclear. MicroRNAs (miRNAs or miRs) are small non-coding RNA molecules that …

Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments

L Zuo, F He, GG Sergakis… - … of Physiology-Lung …, 2014 - journals.physiology.org
Cigarette smoking (CS) can impact the immune system and induce pulmonary disorders
such as chronic obstructive pulmonary disease (COPD), which is currently the fourth leading …

Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted

KJ Greenlee, Z Werb… - Physiological reviews, 2007 - journals.physiology.org
The matrix metalloproteinases (MMPs), a family of 25 secreted and cell surface-bound
neutral proteinases, process a large array of extracellular and cell surface proteins under …

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

ZH Chen, HP Kim, FC Sciurba, SJ Lee… - PloS one, 2008 - journals.plos.org
Background Chronic obstructive pulmonary disease (COPD) is a progressive lung disease
characterized by abnormal cellular responses to cigarette smoke, resulting in tissue …