Reflections on a Career in Pediatric Neuropathology, with a Note of Gratitude

HC Kinney - Annual Review of Pathology: Mechanisms of …, 2025 - annualreviews.org
I am honored to be asked by the journal to write this personal essay about my career in
pediatric neuropathology—a life of immense satisfaction, meaning, and fulfillment. My …

Dysregulation of platelet serotonin, 14–3–3, and GPIX in sudden infant death syndrome

AL Frelinger III, RL Haynes, RD Goldstein… - Scientific Reports, 2024 - nature.com
Sudden infant death syndrome (SIDS) is the leading cause of post-neonatal infant mortality,
but the underlying cause (s) are unclear. A subset of SIDS infants has abnormalities in the …

Platelet Pathophysiology: Unexpected New Research Directions

AD Michelson, AL Frelinger III… - … in Thrombosis and …, 2024 - thieme-connect.com
2023. But why study platelet physiology? Because these remarkable little cells play key
roles in many important pathophysiological processes, including thrombosis, hemorrhage …

Brainstem Encephalitis as a Cause of Sudden Infant Death Syndrome

A Nath - JAMA neurology, 2024 - jamanetwork.com
Sudden unexpected infant death or sudden infant death syndrome (SIDS) are terms used for
children younger than 1 year of age who die suddenly without an obvious cause before …

Neonatal Chlamydia muridarum respiratory infection causes neuroinflammation within the brainstem during the early postnatal period

KE Hedley, HM Gomez, E Kecelioglu… - Journal of …, 2024 - Springer
Respiratory infections are one of the most common causes of illness and morbidity in
neonates worldwide. In the acute phase infections are known to cause wide-spread …

Targeted whole-viral genome sequencing from formalin-fixed paraffin-embedded neuropathology specimens

C Gorißen, A Albers, V Ruf, E Chteinberg… - Acta …, 2024 - Springer
Viral infections of the central nervous system (CNS) can be severe and potentially life-
threatening diseases [4]. Precise detection of the causative pathogen is crucial for definite …

[HTML][HTML] Why do pacifiers/dummies have a protective effect in sudden infant death Syndrome? A new hypothesis

PN Goldwater - Medical Hypotheses, 2024 - Elsevier
Abstract The American Academy of Pediatrics recommends pacifier/dummy use to help
prevent sudden infant death syndrome (SIDS). This recommendation is based on studies …

Metabolic acidosis and sudden infant death syndrome: overlooked data provides insight into SIDS pathogenesis

PN Goldwater, DJ Gebien - World Journal of Pediatrics, 2024 - Springer
Background Decades of mainstream SIDS research based on the Triple Risk Model and
neuropathological findings have failed to provide convincing evidence for a primary CNS …

Illumina and Nanopore sequencing in culture-negative samples from suspected lower respiratory tract infection patients

L Ma, C Zhu, T Yan, Y Hu, J Zhou, Y Li, F Du… - Frontiers in Cellular …, 2024 - frontiersin.org
Objective To evaluate the diagnostic value of metagenomic sequencing technology based
on Illumina and Nanopore sequencing platforms for patients with suspected lower …

[HTML][HTML] Brainstem inflammation in sudden unexpected death in infancy and childhood (SIDS/SUDC)

H Budka, DU Risser, FC Monticelli - Free Neuropathology, 2024 - ncbi.nlm.nih.gov
Sudden Unexpected Infant Death (SUID) is the leading cause of death in the first year of age
in developed countries [4] and a mystery in medicine still to be clarified. Its major component …