There are known sex specific differences in fetal and neonatal morbidity and mortality. There
are also known differences in birthweight centile with males generally being larger than …

The “fetal origin of adult disease Hypothesis” originally described by Barker et al. identified
the relationship between impaired in utero growth and adult cardiovascular disease risk and …

Small non‐coding microRNAs (miRNAs) contribute to cancer development and progression,
and are differentially expressed in normal tissues and cancers. However, the specific role of …

Background Crohn's disease (CD) and ulcerative colitis (UC) are associated with expression
differences in genes involved in immune function, wound healing, and tissue remodeling …

Background MicroRNAs (miRNAs) are small, noncoding RNAs that negatively regulate gene
expression by binding to target mRNAs. miRNAs have not been comprehensively studied in …

Circulating microRNAs (miRNAs) have emerged as candidate biomarkers of various
diseases and conditions including malignancy and pregnancy. This approach requires …

The extracellular matrix (ECM) plays an important role in determining cell and organ
function:(1) it is an organizing substrate that provides tissue tensile strength;(2) it anchors …

In this review we discuss specific examples of regulation of cytokine genes and focus on a
new mechanism involving post-transcriptional regulation via miRNAs. The post …

Abstract Progesterone (P4) and estradiol-17β (E2) play critical and opposing roles in
regulating myometrial quiescence and contractility during pregnancy and labor. Although …

The maintenance of myometrial quiescence and initiation of contractility, which lead to
parturition at term and preterm, involve a shifting equilibrium between anti-inflammatory and …