Colorectal cancer (CRC) is the most common cancer of the digestive system with high
mortality and morbidity rates. Gut microbiota is found in the intestines, especially the …

In brief Sex differences in the gut microbiome may impact multiple aspects of human health
and disease. In this study, we review the evidence for microbial sex differences in puberty …

Nonalcoholic fatty liver disease (NAFLD) is usually characterized with disrupted bile acid
(BA) homeostasis. However, the exact role of certain BA in NAFLD is poorly understood …

Background Low birth weight (LBW) is associated with intestinal inflammation and dysbiosis
after birth. However, the underlying mechanism remains largely unknown. Objective In the …

Although emerging evidence shows that gut microbiota-mediated metabolic changes
regulate intestinal pathogen invasions, little is known about whether and how gut microbiota …

The intestinal barrier, composed of the luminal microbiota, the mucus layer, and the physical
barrier consisting of epithelial cells and immune cells, the latter residing underneath and …

Background Altered intestinal microbiota composition in later life is associated with
inflammaging, declining tissue function, and increased susceptibility to age-associated …

Background and purpose Stroke is associated with high disability and mortality rates and
increases the incidence of organ-related complications. Research has revealed that the …

Circadian rhythms are biological systems that synchronize cellular circadian oscillators with
the organism's daily feeding-fasting or rest-activity cycles in mammals. Circadian rhythms …

Aging is an inevitable biochemical process that adversely affects personal health and poses
ever-increasing challenges to society. Recent research has revealed the crucial role of …