Progress in acute myeloid leukaemia treatment is occurring at an unprecedented pace. The
past decade has witnessed an increasingly improved scientific understanding of the …

Background: Acute myeloid leukemia (AML) is a disease of the hematopoietic system that
remains a therapeutic challenge despite advances in our understanding of the underlying …

For most acute myeloid leukemia (AML) patients an allogeneic hematopoietic stem cell
transplantation (HSCT) offers the highest chance of cure. The introduction of less toxic non …

The use of measurable residual disease (MRD) as a biomarker for prognostication, risk
stratification, and therapeutic decision-making in acute myeloid leukemia (AML) is gaining …

NGS has proven to be a useful approach for the analysis of genomic alterations in patients
with AML, which aids patient management. Current research is being directed at reducing …

Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapy
for many hematologic malignancies as well as non-malignant conditions. Part of the curative …

* Correspondence: moxiaodong@ bjmu. edu. cn (XM); hxx12276@ rjh. com. cn (XH)
Received: May 11, 2023; Accepted: June 18, 2023; Published Online: June 20, 2023; …

Measurable residual disease (MRD) has been widely recognized as a biomarker for deeply
evaluating complete remission (CR), predicting relapse, guiding pre-emptive interventions …

Over the past decade, our understanding of AML pathogenesis and pathophysiology has
improved significantly with mutational profiling. This has led to translational advances in …

Simple Summary Advances in immunophenotyping and molecular techniques have allowed
for the development of more sensitive diagnostic tests in acute leukemia. These techniques …