Infections represent a common health problem in people of all ages. Usually, the response
given to them is appropriate and so little treatment is needed. Sometimes, however, the …

Bloodstream infections are a major concern because of high levels of antibiotic consumption
and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a …

Biomarkers have great potential to improve the diagnosis and treatment of sepsis. The
available literature supports the potential utility of sTREM-1, IL-27, suPAR, neutrophil CD64 …

Modern burn care has led to unprecedented survival rates in burn patients whose injuries
were fatal a few decades ago. Along with improved survival, new challenges have emerged …

Background In resource limited settings acute febrile illnesses are often treated empirically
due to a lack of reliable, rapid point-of-care diagnostics. This contributes to the …

Infections occur frequently in critically ill patients and their management can be challenging
for various reasons, including delayed diagnosis, difficulties identifying causative …

Neonatal early-onset sepsis (EOS) is defined as an invasive infection that occurs in the first
72 h of life. The incidence of EOS varies from 0.5–2% live births in developed countries, up …

Respiratory tract infections require early diagnosis and adequate treatment. With the
antibiotic overuse and increment in antibiotic resistance there is an increased need to …

Biomarkers as C-reactive protein (CRP) and procalcitonin (PCT) emerged as tools to help
clinicians to diagnose infection and to properly initiate and define the duration of antibiotic …

The scourge of antibiotic resistance threatens modern healthcare delivery. A contributing
factor to this significant issue may be antibiotic dosing, whereby standard antibiotic regimens …