Chalcones belong to the flavonoid family which constitutes one of the major classes of
naturally occurring oxygen heterocyclic compounds. The α, β-unsaturated carbonyl system …

The human body is under constant attack from oxidative stress which in turn induces the
excessive production of free radicals, particularly the reactive oxygen species in the body …

Some novel 1, 3, 4-trisubstituted pyrazoles were synthesized and screened for their anti-
inflammatory and analgesic activities as well as their ulcerogenic liability. They showed anti …

To enhance the cytotoxicity of benzimidazole and/or benzoxazole core, the benzimidazole/
benzoxazole azo-pyrimidine were synthesized through diazo-coupling of 3 …

The pyrimidine moiety is one of the most widespread heterocycles in biologically occurring
compounds, such as nucleic acids components (uracil, thymine and cytosine) and vitamin …

Chalcones were synthesized by reacting indole-3-aldehyde, prepared by Vilsemeir Haack
reaction with 4-substituted acetophenone in ethanolic KOH solution. These chalcones were …

Background: Free radicals are frequently generated in vivo and their reactivity varies
causing different damages to biological molecules, eg DNA, lipids, and proteins. Oxidative …

A new pyrimidine derivative Schiff base (HL)[HL= 2-((4-amino-6-chloropyrimidin-2-ylimino)
methyl)-4-nitrophenol] has been synthesized using 2, 6-diamino-4-chloropyrimidine and 5 …

Sažetak A series of 1, 8-dihydro-1-aryl-8-alkyl pyrazolo (3, 4-b) indoles 4a-j, 5a-j and 6a-j
has been synthesized and tested for their anti-inflammatory and anticonvulsant activities …

Because of the great biological importance of substituted indole derivatives, in the present
study, a series of pyrazolylindole, thiazolylindole, and pyrimidinylindole derivatives have …