Roles of microglia in brain development, tissue maintenance and repair

MA Michell-Robinson, H Touil, LM Healy, DR Owen… - Brain, 2015 - academic.oup.com
The emerging roles of microglia are currently being investigated in the healthy and diseased
brain with a growing interest in their diverse functions. In recent years, it has been …

MicroRNAs in neuronal function and dysfunction

HI Im, PJ Kenny - Trends in neurosciences, 2012 - cell.com
MicroRNAs (miRNAs) are small noncoding RNA transcripts expressed throughout the brain
that can regulate neuronal gene expression at the post-transcriptional level. Here, we …

Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia

MR Hutchinson, Y Shavit, PM Grace, KC Rice… - Pharmacological …, 2011 - Elsevier
Vastly stimulated by the discovery of opioid receptors in the early 1970s, preclinical and
clinical research was directed at the study of stereoselective neuronal actions of opioids …

Current understanding of HIV-associated neurocognitive disorders pathogenesis

P Gannon, MZ Khan, DL Kolson - Current opinion in neurology, 2011 - journals.lww.com
Prevention and treatment of HAND requires strategies aimed at suppressing CNS HIV
replication and effects of systemic and CNS inflammation in aging and substance-abusing …

Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring

FCR Zucchi, Y Yao, ID Ward, Y Ilnytskyy, DM Olson… - PloS one, 2013 - journals.plos.org
The gestational state is a period of particular vulnerability to diseases that affect maternal
and fetal health. Stress during gestation may represent a powerful influence on maternal …

Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated neuronal dysfunction

G Hu, H Yao, AD Chaudhuri, M Duan… - Cell death & …, 2012 - nature.com
Neuronal damage is a hallmark feature of HIV-associated neurological disorders (HANDs).
Opiate drug abuse accelerates the incidence and progression of HAND; however, the …

Morphine as a potential oxidative stress-causing agent

J Skrabalova, Z Drastichova… - Mini-reviews in organic …, 2013 - ingentaconnect.com
Morphine exhibits important pharmacological effects for which it has been used in medical
practice for quite a long time. However, it has a high addictive potential and can be abused …

Fast-track surgery decreases the incidence of postoperative delirium and other complications in elderly patients with colorectal carcinoma

Y Jia, G Jin, S Guo, B Gu, Z Jin, X Gao, Z Li - Langenbeck's archives of …, 2014 - Springer
Objective This study aims to investigate the role of fast-track surgery in preventing the
development of postoperative delirium and other complications in elderly patients with …

MicroRNA-15b modulates Japanese encephalitis virus–mediated inflammation via targeting RNF125

B Zhu, J Ye, Y Nie, U Ashraf, A Zohaib… - The Journal of …, 2015 - journals.aai.org
Japanese encephalitis virus (JEV) can target CNS and cause neuroinflammation that is
characterized by profound neuronal damage and concomitant microgliosis/astrogliosis …

Stress-and drug-induced neuroimmune signaling as a therapeutic target for comorbid anxiety and substance use disorders

CE Smiley, SK Wood - Pharmacology & therapeutics, 2022 - Elsevier
Stress and substance use disorders remain two of the most highly prevalent psychiatric
conditions and are often comorbid. While individually these conditions have a debilitating …