Genome-wide association studies

E Uffelmann, QQ Huang, NS Munung… - Nature Reviews …, 2021 - nature.com
Genome-wide association studies (GWAS) test hundreds of thousands of genetic variants
across many genomes to find those statistically associated with a specific trait or disease …

Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

[HTML][HTML] Genome-wide association studies in ancestrally diverse populations: opportunities, methods, pitfalls, and recommendations

RE Peterson, K Kuchenbaecker, RK Walters, CY Chen… - Cell, 2019 - cell.com
Genome-wide association studies (GWASs) have focused primarily on populations of
European descent, but it is essential that diverse populations become better represented …

The ancestral and industrialized gut microbiota and implications for human health

ED Sonnenburg, JL Sonnenburg - Nature Reviews Microbiology, 2019 - nature.com
Human-associated microbial communities have adapted to environmental pressures. Doses
of antibiotics select for a community with increased antibiotic resistance, inflammation is …

Why are people antiscience, and what can we do about it?

A Philipp-Muller, SWS Lee… - Proceedings of the …, 2022 - National Acad Sciences
From vaccination refusal to climate change denial, antiscience views are threatening
humanity. When different individuals are provided with the same piece of scientific evidence …

Rights, interests and expectations: Indigenous perspectives on unrestricted access to genomic data

M Hudson, NA Garrison, R Sterling, NR Caron… - Nature Reviews …, 2020 - nature.com
Addressing Indigenous rights and interests in genetic resources has become increasingly
challenging in an open science environment that promotes unrestricted access to genomic …

Ethics of DNA research on human remains: five globally applicable guidelines

S Alpaslan-Roodenberg, D Anthony, H Babiker… - Nature, 2021 - nature.com
We are a group of archaeologists, anthropologists, curators and geneticists representing
diverse global communities and 31 countries. All of us met in a virtual workshop dedicated to …

Museum genomics

DC Card, B Shapiro, G Giribet, C Moritz… - Annual Review of …, 2021 - annualreviews.org
Natural history collections are invaluable repositories of biological information that provide
an unrivaled record of Earth's biodiversity. Museum genomics—genomics research using …

[HTML][HTML] Addressing underrepresentation in genomics research through community engagement

AA Lemke, ED Esplin, AJ Goldenberg… - The American Journal of …, 2022 - cell.com
The vision of the American Society of Human Genetics (ASHG) is that people everywhere
will realize the benefits of human genetics and genomics. Implicit in that vision is the …

Early human dispersals within the Americas

JV Moreno-Mayar, L Vinner, P de Barros Damgaard… - Science, 2018 - science.org
INTRODUCTION Genetic studies of the Pleistocene peopling of the Americas have focused
on the timing and number of migrations from Siberia into North America. They show that …