Neural stem cells (NSCs) undergo massive molecular and cellular changes during neuronal
differentiation. These include mitochondria and metabolism remodelling, which were …

Metabolism has emerged as a key regulator of stem cell behavior. Mitochondria are crucial
metabolic organelles that are important for differentiated cells, yet considered less so for …

The beneficial effects of physical activity on brain ageing are well recognised, with
exerkines, factors that are secreted into the circulation in response to exercise, emerging as …

In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

The extent to which neurogenesis occurs in adult primates remains controversial. In this
study, using an optimized single-cell RNA sequencing pipeline, we profiled 207,785 cells …

Although the neurogenesis-enhancing effects of exercise have been extensively studied, the
molecular mechanisms underlying this response remain unclear. Here, we propose that this …

Reactive oxygen species (ROS) at the right concentration promote cell proliferation in cell
culture, stem cells, and model organisms. However, the mystery of how ROS signaling is …

Neural stem/progenitor cells (NSPCs) generate new neurons throughout adulthood.
However, the underlying regulatory processes are still not fully understood. Lipid …

Simple Summary According to Globocan 2020 data, approximately 308,102 new cases of
brain cancer and central nervous system (CNS) cancers were reported worldwide, with …

Understanding the mechanisms behind neurodifferentiation in adults will be an important
milestone in our quest to identify treatment strategies for cognitive disorders observed during …