A higher incidence of colorectal cancer (CRC) is found in males compared to females.
Young women (18–44 years) with CRC have a better survival outcome compared to men of …

As early as the 1800s, the actions of estrogen have been implicated in the development and
progression of breast cancer. The estrogen receptor (ER) was identified in the late 1950s …

The capability of 17β‐estradiol (E2) to induce the non‐genomic activities of its receptors
(ERα and ERβ) and to evoke different signaling pathways committed to the regulation of cell …

BACKGROUND Various studies have reported an inverse relation between oral
contraceptive (OC) use and the risk of colorectal cancer, but the issue is still open …

Sex significantly influences the clinical and pathological characteristics of colorectal cancer
(CRC). These include differences in incidence and mortality rates, clinical presentations …

Quercetin, the major constituent of flavonoid and widely present in fruits and vegetables, is
an attractive compound for cancer prevention due to its beneficial anti proliferative effects …

Phytoestrogens are natural substances that have been extensively studied for their
beneficial effect on human health. Herein, we analyzed the data of the literature on the role …

Objectives Sporadic colorectal cancer (CRC) is considered a multifactorial disease where
multiple exposures interact with the individual genetic background resulting in risk …

The flavanone naringenin (Nar), especially abundant in the Mediterranean diet, is reported
to have anti‐proliferative effects in many cancer cell lines. Antioxidant activities, kinase and …

A link between unsaturated fatty acids or phytonutrients and reduced risk of colorectal
cancer has been suggested. However, the effects of higher intake of dietary sources of these …