Lung ventilation fluctuates widely with behavior but arterial PCO 2 remains stable. Under
normal conditions, the chemoreflexes contribute to PaCO 2 stability by producing small …

CENTRAL CHEMORECEPTION refers to detection of CO2/pH within the brain and the
subsequent reflex effects on breathing. It involves multiple sites within the hindbrain (9, 12 …

Vagus nerve stimulation (VNS) paired with forelimb training drives robust, specific
reorganization of movement representations in the motor cortex. This effect is hypothesized …

Serotonin (5-HT) is a neuromodulator–transmitter influencing global brain function. Past and
present findings illustrate a prominent role for 5-HT in the modulation of ponto-medullary …

The 'distributed chemoreception theory'attributes the central chemoreflex (the stimulation of
breathing by CNS acidification) to the cumulative effects of pH on multiple classes of …

Serotonergic (5-HT) neurons are putative central respiratory chemoreceptors, aiding in the
brain's ability to detect arterial changes in [Formula: see text] and implement appropriate …

Psychedelics (serotonergic hallucinogens) are psychoactive substances that can alter
perception and mood, and affect cognitive functions. These substances activate 5-HT 2A …

Serotonin activates respiration and enhances the stimulatory effect of CO2 on breathing. The
present study tests whether the mechanism involves the retrotrapezoid nucleus (RTN), a …

The term ribosome-inactivating protein (RIP) is used to denominate proteins mostly of plant
origin, which have N-glycosidase enzymatic activity leading to a complete destruction of the …

µ-Opioid receptors (MORs) are responsible for mediating both the analgesic and respiratory
effects of opioid drugs. By binding to MORs in brainstem regions involved in controlling …