Functions of neurotrophins and growth factors in neurogenesis and brain repair

SLB Oliveira, MM Pillat, A Cheffer, C Lameu… - Cytometry Part …, 2013 - Wiley Online Library
The identification and isolation of multipotent neural stem and progenitor cells in the brain,
giving rise to neurons, astrocytes, and oligodendrocytes initiated many studies in order to …

Interplay between nitric oxide and brain-derived neurotrophic factor in neuronal plasticity

C Biojone, P Cabrera Casarotto… - CNS & Neurological …, 2015 - ingentaconnect.com
Nitric oxide is a gaseous neuromodulator that displays a core role in several neuronal
processes. Beyond regulating the release of neurotransmitters, nitric oxide also plays a role …

[HTML][HTML] nNOS-induced tyrosine nitration of TRKB impairs BDNF signaling and restrains neuronal plasticity

C Biojone, PC Casarotto, C Cannarozzo, SM Fred… - Progress in …, 2023 - Elsevier
Nitric oxide (NO) has been long recognized as an important modulator of neural plasticity,
but characterization of the molecular mechanisms involved-specially the guanylyl cyclase …

[HTML][HTML] Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide–mediated dysregulation of claudin expression

J Kho, U Polak, MM Jiang, JD Odom, JV Hunter… - JCI insight, 2023 - ncbi.nlm.nih.gov
Nitric oxide (NO) is a critical signaling molecule that has been implicated in the
pathogenesis of neurocognitive diseases. Both excessive and insufficient NO production …

Expanding the phenotype in argininosuccinic aciduria: need for new therapies

J Baruteau, E Jameson, AA Morris… - Journal of Inherited …, 2017 - Wiley Online Library
Objectives This UK‐wide study defines the natural history of argininosuccinic aciduria and
compares long‐term neurological outcomes in patients presenting clinically or treated …

Glucagon-like peptide-1 excites firing and increases GABAergic miniature postsynaptic currents (mPSCs) in gonadotropin-releasing hormone (GnRH) neurons of the …

I Farkas, C Vastagh, E Farkas, F Bálint… - Frontiers in cellular …, 2016 - frontiersin.org
Glucagon-like peptide-1 (GLP-1), a metabolic signal molecule, regulates reproduction,
although, the involved molecular mechanisms have not been elucidated, yet. Therefore …

Kinin and purine signaling contributes to neuroblastoma metastasis

H Ulrich, MZ Ratajczak, G Schneider… - Frontiers in …, 2018 - frontiersin.org
Bone marrow metastasis occurs in approximately 350,000 patients that annually die in the
US alone. In view of the importance of tumor cell migration into the bone marrow, we have …

Neurogenic and neuro-protective potential of a novel subpopulation of peripheral blood-derived CD133+ ABCG2+ CXCR4+ mesenchymal stem cells: development of …

JE Nichols, JA Niles, D DeWitt, D Prough… - Stem cell research & …, 2013 - Springer
Introduction Nervous system injuries comprise a diverse group of disorders that include
traumatic brain injury (TBI). The potential of mesenchymal stem cells (MSCs) to differentiate …

L-Citrulline Protects Skeletal Muscle Cells from Cachectic Stimuli through an iNOS-Dependent Mechanism

DJ Ham, BG Gleeson, A Chee, DM Baum, MK Caldow… - PLoS …, 2015 - journals.plos.org
Dietary L-citrulline is thought to modulate muscle protein turnover by increasing L-arginine
availability. To date, the direct effects of increased L-citrulline concentrations in muscle have …

Effect of BDNF and Other Potential Survival Factors in Models of In Vitro Oxidative Stress on Adult Spinal Cord–Derived Neural Stem/Progenitor Cells

LD Hachem, AJ Mothe, CH Tator - BioResearch open access, 2015 - liebertpub.com
Transplantation of neural stem/progenitor cells (NSPCs) is a promising strategy in spinal
cord injury (SCI). However, poor survival of transplanted stem cells remains a major …