Characterization of nanoparticles-based vaccines for COVID-19

G Guerrini, D Magrì, S Gioria, D Medaglini… - Nature …, 2022 - nature.com
Several vaccines against COVID-19 use nanoparticles to protect the antigen cargo (either
proteins or nucleic acids), increase the immunogenicity and ultimately the efficacy. The …

[HTML][HTML] Nanovaccines: a game changing approach in the fight against infectious diseases

MAH Abusalah, H Chopra, A Sharma… - Biomedicine & …, 2023 - Elsevier
The field of nanotechnology has revolutionised global attempts to prevent, treat, and
eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a …

Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses

T Mao, B Israelow, MA Peña-Hernández, A Suberi… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
highlighted the need for vaccines that not only prevent disease but also prevent …

Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters

G Nouailles, JM Adler, P Pennitz, S Peidli… - Nature …, 2023 - nature.com
Vaccines play a critical role in combating the COVID-19 pandemic. Future control of the
pandemic requires improved vaccines with high efficacy against newly emerging SARS-CoV …

Safety and immunogenicity of the chlamydia vaccine candidate CTH522 adjuvanted with CAF01 liposomes or aluminium hydroxide: a first-in-human, randomised …

S Abraham, HB Juel, P Bang… - The Lancet infectious …, 2019 - thelancet.com
Background Chlamydia is the most common sexually transmitted bacterial infection
worldwide. National screening programmes and antibiotic treatment have failed to decrease …

Role of the microbiota in the modulation of vaccine immune responses

A Ciabattini, R Olivieri, E Lazzeri… - Frontiers in …, 2019 - frontiersin.org
The human immune system and the microbiota co-evolve, and their balanced relationship is
based on crosstalk between the two systems through the course of life. This tight association …

Modulation of primary immune response by different vaccine adjuvants

A Ciabattini, E Pettini, F Fiorino, G Pastore… - Frontiers in …, 2016 - frontiersin.org
Adjuvants contribute to enhancing and shaping the vaccine immune response through
different modes of action. Here early biomarkers of adjuvanticity after primary immunization …

Novel hydrogel-forming microneedle array for intradermal vaccination in mice using ovalbumin as a model protein antigen

AJ Courtenay, AM Rodgers… - Molecular …, 2018 - ACS Publications
Global vaccination strategies have traditionally relied on the hypodermic needle and syringe
model. However, to facilitate increased immunization coverage and reduce costs, novel …

[HTML][HTML] Vaccine-induced antigen-specific regulatory T cells attenuate the antiviral immunity against acute influenza virus infection

PH Lin, WI Wong, YL Wang, MP Hsieh, C Lu… - Mucosal …, 2018 - Elsevier
Peptide-based T cell vaccines targeting the conserved epitopes of influenza virus can
provide cross-protection against distantly related strains, but they are generally not …

Prime-pull vaccination with a plant-derived virus-like particle influenza vaccine elicits a broad immune response and protects aged mice from death and frailty after …

B Hodgins, S Pillet, N Landry, BJ Ward - Immunity & Ageing, 2019 - Springer
Background Administered intramuscularly (IM), plant-derived, virus-like-particle (VLP)
vaccines based on the influenza hemagglutinin (HA) protein elicit both humoral and cellular …