Understanding esophageal cancer: the challenges and opportunities for the next decade

J Yang, X Liu, S Cao, X Dong, S Rao, K Cai - Frontiers in oncology, 2020 - frontiersin.org
Esophageal cancer (EC) is the seventh most common cancer worldwide with over 570,000
new cases annually. In China, the incidence of EC is particularly high where approximately …

[HTML][HTML] The role of ALDH2 in tumorigenesis and tumor progression: Targeting ALDH2 as a potential cancer treatment

H Zhang, L Fu - Acta Pharmaceutica Sinica B, 2021 - Elsevier
A major mitochondrial enzyme for protecting cells from acetaldehyde toxicity is aldehyde
dehydrogenase 2 (ALDH2). The correlation between ALDH2 dysfunction and …

Cancer situation in China: what does the China cancer map indicate from the first national death survey to the latest cancer registration?

R Feng, Q Su, X Huang, T Basnet, X Xu… - Cancer …, 2023 - Wiley Online Library
Background Over the past four decades, the Chinese government has conducted three
surveys on the distribution of causes of death and built cancer registration. In order to shine …

ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH/PSAT1/serine metabolic pathway

S Li, H Yang, W Li, J Liu, L Ren, Y Yang, B Ge… - Acta Pharmacologica …, 2022 - nature.com
Colorectal cancer (CRC) is the third most common cancer in men and the second most
common cancer in women worldwide. CRC is the second leading cause of cancer-related …

Overview of risk factors for esophageal squamous cell carcinoma in China

E Conway, H Wu, L Tian - Cancers, 2023 - mdpi.com
Simple Summary Esophageal cancer holds the rank of 6th highest mortality rate worldwide
and carries a low survival rate of 10–30%. The pathology type of esophageal squamous cell …

Intracellular kynurenine promotes acetaldehyde accumulation, further inducing the apoptosis in soil beneficial fungi Trichoderma guizhouense NJAU4742 under acid …

H Zhu, T Li, C Li, Y Liu, Y Miao, D Liu… - Environmental …, 2023 - Wiley Online Library
In this study, the growth of fungi Trichoderma guizhouense NJAU4742 was significantly
inhibited under acid stress, and the genes related to acid stress were identified based on …

Role of microbial dysbiosis in carcinogenesis & cancer therapies

J Vimal, I Himal, S Kannan - Indian Journal of Medical Research, 2020 - journals.lww.com
The human body supports a heterogeneous population of microorganisms. Every
microorganism has the ability to contribute to the unique microenvironment around it. The …

The Human Body as an Ethanol-Producing Bioreactor—The Forensic Impacts

I Šoša - Fermentation, 2023 - mdpi.com
Auto-brewery syndrome (ABS), also called gut fermentation syndrome, is an extremely
infrequent but also underrecognized disorder where ethanol is produced endogenously …

The roles of drug metabolism-related ADH1B in immune regulation and therapeutic response of ovarian cancer

Z Xu, B Peng, F Kang, W Zhang, M Xiao, J Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Background: The different pharmacological effects of drugs in different people can be
explained by the polymorphisms of drug metabolism-related genes. Emerging studies have …

大型人群队列遗传资源建设与利用

陈兴栋, 蒋艳峰, 徐萍, 金力 - 遗传, 2021 - chinagene.cn
在大数据和精准医学的时代, 大型人群队列研究是慢性病病因研究的首选设计之一,
队列遗传资源已成为我国重要的战略资源. 推动队列遗传资源的标准化建设与利用可有效促进 …