The typical pattern of morphological evolution associated with the radiation of a group of
related species is the emergence of a novel trait and its subsequent diversification. Yet the …

Germ-line transformation of insects is now possible with four independent transposable
element vector systems. Among these, the TTAA-insertion site specific transposon …

Genetic engineering technologies can be used both to create transgenic mosquitoes
carrying antipathogen effector genes targeting human malaria parasites and to generate …

Reversible acetylation of α-tubulin has been implicated in regulating microtubule stability
and function. The distribution of acetylated α-tubulin is tightly controlled and stereotypic …

Transposable elements have been routinely used for genetic manipulation in lower
organisms, including generating transgenic animals and insertional mutagenesis. In …

We present a new approach to genotyping based on multiplexed shotgun sequencing that
can identify recombination breakpoints in a large number of individuals simultaneously at a …

Dengue and dengue hemorrhagic fever are increasing public health problems with an
estimated 50–100 million new infections each year. Aedes aegypti is the major vector of …

Malaria is estimated to cause 0.7 to 2.7 million deaths per year, but the actual figures could
be substantially higher owing to under-reporting and difficulties in diagnosis. If no new …

We have generated a recombinant Mos1 transposon that can insert up to 45-kb transgenes
into the Caenorhabditis elegans genome. The minimal Mos1 transposon (miniMos) is 550 …

Fundamental and applied studies of silkworms have entered the functional genomics era.
Here, we report a multi-gene expression system (MGES) based on 2A self-cleaving peptide …