Proton-dependent multidrug efflux systems
IT Paulsen, MH Brown, RA Skurray - Microbiological reviews, 1996 - Am Soc Microbiol
Multidrug efflux systems display the ability to transport a variety of structurally unrelated
drugs from a cell and consequently are capable of conferring resistance to a diverse range …
drugs from a cell and consequently are capable of conferring resistance to a diverse range …
Fungal transporters involved in efflux of natural toxic compounds and fungicides
G Del Sorbo, H Schoonbeek, MA De Waard - Fungal genetics and biology, 2000 - Elsevier
Survival of microorganisms in natural environments is favored by the capacity to produce
compounds toxic to competing organisms and the ability to resist the effects of such toxic …
compounds toxic to competing organisms and the ability to resist the effects of such toxic …
Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals
R Prasad, P De Wergifosse, A Goffeau, E Balzi - Current genetics, 1995 - Springer
By functional complementation of a PDR5 null mutant of Saccharomyces cervisiae, we have
cloned and sequenced the multidrug-resistance gene CDR1 of Candida albicans …
cloned and sequenced the multidrug-resistance gene CDR1 of Candida albicans …
A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole
D Calabrese, J Bille, D Sanglard - Microbiology, 2000 - microbiologyresearch.org
Azole resistance in Candida albicans can be mediated by several resistance mechanisms.
Among these, alterations of the azole target enzyme and the overexpression of multidrug …
Among these, alterations of the azole target enzyme and the overexpression of multidrug …
Multidrug‐resistant transport proteins in yeast: complete inventory and phylogenetic characterization of yeast open reading frames within the major facilitator …
A Goffeau, J Park, IT Paulsen, JLUC JONNIAUX… - Yeast, 1997 - Wiley Online Library
Screening of the complete genome sequence from the yeast Saccharomyces cerevisiae
reveals that 28 open reading frames (ORFs) are homologous to each other and to …
reveals that 28 open reading frames (ORFs) are homologous to each other and to …
Genetics and biochemistry of yeast multidrug resistance
E Balzi, A Goffeau - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1994 - Elsevier
The development of resistance to a wide range of unrelated cytotoxic compounds is a
common phenomenon observed in various organisms throughout the evolutionary scale …
common phenomenon observed in various organisms throughout the evolutionary scale …
Multidrug resistance in Candida albicans: disruption of the BENr gene
M Goldway, D Teff, R Schmidt… - Antimicrobial agents …, 1995 - Am Soc Microbiol
The BENr gene of Candida albicans, which confers resistance on susceptible strains of
Saccharomyces cerevisiae to six structurally and functionally unrelated drugs, was …
Saccharomyces cerevisiae to six structurally and functionally unrelated drugs, was …
Proteome scale census of major facilitator superfamily transporters in Trichoderma reesei using protein sequence and structure based classification enhanced ranking
Trichoderma spp. have been acknowledged as potent bio-control agents against microbial
pathogens and also as plant growth promoters. Various secondary metabolites are …
pathogens and also as plant growth promoters. Various secondary metabolites are …
FLR1 gene (ORF YBR008c) is required for benomyl and methotrexate resistance in Saccharomyces cerevisiae and its benomyl‐induced expression is dependent on …
In this work we report the disruption of a Saccharomyces cerevisiae ORF YBR008c (FLR1
gene) within the context of EUROFAN (EUROpean Functional Analysis Network) six‐pack …
gene) within the context of EUROFAN (EUROpean Functional Analysis Network) six‐pack …
Drug resistance in yeasts—an emerging scenario
R Prasad, SL Panwar - 2002 - Elsevier
In view of the increasing threat posed by fungal infections in immunocompromised patients
and due to the non-availability of effective treatments, it has become imperative to find novel …
and due to the non-availability of effective treatments, it has become imperative to find novel …