Alternative animal models in predictive toxicology

MNH Khabib, Y Sivasanku, HB Lee, S Kumar, CS Kue - Toxicology, 2022 - Elsevier
Toxicity testing relies heavily on animals, especially rodents as part of the non-clinical
laboratory testing of substances. However, the use of mammalians and the number of …

[HTML][HTML] Novel synthetic UV screen compounds inspired in mycosporine-like amino acids (MAAs): Antioxidant capacity, photoprotective properties and toxicity

FL Figueroa, P Castro-Varela, J Vega… - … of Photochemistry and …, 2024 - Elsevier
The combination of environmental stress on the ozone layer, climate change and a greater
sun exposure due to outdoor habits has led to an increase in skin cancer cases and other …

Cytotoxicity of seaweed compounds, alone or combined to reference drugs, against breast cell lines cultured in 2D and 3D

F Malhão, AA Ramos, AC Macedo, E Rocha - Toxics, 2021 - mdpi.com
Seaweed bioactive compounds have shown anticancer activities in in vitro and in vivo
studies. However, tests remain limited, with conflicting results, and effects in combination …

Antioxidant activity and zebrafish teratogenicity of hydroalcoholic Moringa oleifera L. leaf extracts

NFS Mohamad Shariff, T Singgampalam, CH Ng… - British Food …, 2020 - emerald.com
Purpose Moringa oleifera (MO) is a herbal remedy that is rich in essential amino acids and
phytochemicals in the leaves, seeds and pods. It is becoming a famous food in various …

In Vitro and In Vivo Effects of Ulvan Polysaccharides from Ulva rigida

J García-Márquez, BR Moreira, P Valverde-Guillén… - Pharmaceuticals, 2023 - mdpi.com
One of the main bioactive compounds of interest from the Ulva species is the sulfated
polysaccharide ulvan, which has recently attracted attention for its anticancer properties …

Differential toxicity and teratogenic effects of the hot water and cold water extracts of Lignosus rhinocerus (Cooke) Ryvarden sclerotium on zebrafish (Danio rerio) …

NA Abd Rashid, BF Lau, CS Kue - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The sclerotium of Lignosus rhinocerus (Cooke) Ryvarden
is highly valued for its purported medicinal properties. The decoction and macerated …

[PDF][PDF] Toxicity Effect ofBougainvillea glabra (Paper Flower) Water Extracts on Zebrafish Embryo

LE Teh, CS Kue, CH Ng, BF Lau - 2019 - pdfs.semanticscholar.org
Background: Bougainvillea glabra, or paper flower, is an ornamental plant known to possess
various pharmacological activities. However, there is little information on the potential …

[PDF][PDF] Hydroalcoholic Moringa oleifera L. Leaf Extracts Ameliorate Alcohol-induced Steatohepatitis in Zebrafish Larvae.

K Arumainathan, SF Kiew, CH Ng… - Malaysian Journal of …, 2023 - medic.upm.edu.my
Introduction: Alcohol consumption for a prolonged duration induces fatty liver disease such
as steatosis. This research aims to examine the bioactive compounds in hydroalcoholic …

Antifouling Properties of Brown Macroalgae Dictyota dichotoma Collected from the Red Sea; Comparison of Surface and Whole Thallus Extracts.

DS Salim Basndwah, M El-Sherbiny… - Journal of King …, 2022 - search.ebscohost.com
The metabolites produced by the marine macroalgae are considered as a source for the
natural product antifoulants. In this study, the surface and whole thallus extracts of the …

[PDF][PDF] Cytotoxicity of Seaweed Compounds, Alone or Combined to Reference Drugs, against Breast Cell Lines Cultured in 2D and 3D. Toxics 2021, 9, 24

F Malhão, AA Ramos, AC Macedo, E Rocha - 2021 - researchgate.net
Seaweed bioactive compounds have shown anticancer activities in in vitro and in vivo
studies. However, tests remain limited, with conflicting results, and effects in combination …