Allergy and allergic diseases

AB Kay - New England Journal of Medicine, 2001 - Mass Medical Soc
Allergic rhinitis, asthma, and atopic eczema are among the commonest causes of chronic ill
health. These diseases are increasing in prevalence, and they add considerably to the …

The recombinant allergen‐based concept of component‐resolved diagnostics and immunotherapy (CRD and CRIT)

VALENTA, LIDHOLM… - Clinical & …, 1999 - search.ebscohost.com
Current forms of allergy diagnosis and specific immunotherapy are performed with allergen
extracts. Allergen extracts contain a variety of allergenic and nonallergenic components and …

Structural and functional aspects of PR‐10 proteins

H Fernandes, K Michalska, M Sikorski… - The FEBS …, 2013 - Wiley Online Library
Physical, chemical and biological stress factors, such as microbial infection, upregulate the
transcription levels of a number of plant genes, coding for the so‐called pathogenesis …

[HTML][HTML] Allergen extracts for in vivo diagnosis and treatment of allergy: is there a future?

R Valenta, A Karaulov, V Niederberger… - The Journal of Allergy …, 2018 - Elsevier
Today, in vivo allergy diagnosis and allergen-specific immunotherapy (AIT) are still based
on allergen extracts obtained from natural allergen sources. Several studies analyzing the …

Update of the WHO/IUIS A llergen N omenclature D atabase based on analysis of allergen sequences

C Radauer, A Nandy, F Ferreira, RE Goodman… - Allergy, 2014 - Wiley Online Library
Abstract The IUIS A llergen N omenclature S ub‐C ommittee, under the auspices of the W
orld H ealth O rganization and the I nternational U nion of I mmunological S ocieties …

Allergic cross‐reactivity: from gene to the clinic

F Ferreira, T Hawranek, P Gruber, N Wopfner, A Mari - Allergy, 2004 - Wiley Online Library
A large number of allergenic proteins have now their complete cDNA sequences determined
and in some cases also the 3D structures. It turned out that most allergens could be grouped …

The future of antigen-specific immunotherapy of allergy

R Valenta - Nature Reviews Immunology, 2002 - nature.com
More than 25% of the population in industrialized countries suffers from immunoglobulin-E-
mediated allergies. The antigen-specific immunotherapy that is in use at present involves …

Nomenclature and structural biology of allergens

MD Chapman, A Pomés, H Breiteneder… - Journal of allergy and …, 2007 - Elsevier
Purified allergens are named using the systematic nomenclature of the Allergen
Nomenclature Sub-Committee of the World Health Organization and International Union of …

Why are some proteins allergens?

RDJ Huby, RJ Dearman, I Kimber - Toxicological sciences, 2000 - academic.oup.com
The ability of certain proteins to induce an allergic response in susceptible individuals is well
established. Symptoms can range from mild erythema or rhinitis, to acute, and possibly fatal …

Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T‐cell …

C Ebner, U Siemann, B Bohle… - Clinical & …, 1997 - Wiley Online Library
Summary Background and Objective The mechanisms operative in specific immunotherapy
(SIT) of Type I allergy are not completely understood. In the present study we evaluated …