Corneal nerves in health and disease

BS Shaheen, M Bakir, S Jain - Survey of ophthalmology, 2014 - Elsevier
Corneal nerves are responsible for the sensations of touch, pain, and temperature and play
an important role in the blink reflex, wound healing, and tear production and secretion …

Ocular toxicity of mustard gas: A concise review

A Fuchs, EA Giuliano, NR Sinha, RR Mohan - Toxicology letters, 2021 - Elsevier
Sulfur mustard (SM) is a chemical warfare agent that has been used throughout recent
history and remains a threat today. Exposed soldiers and civilians experience a variety of …

Insights into mustard gas keratopathy-characterizing corneal layer-specific changes in mice exposed to nitrogen mustard

H Alemi, S Dehghani, K Forouzanfar, PL Surico… - Experimental eye …, 2023 - Elsevier
Exposure to mustard agents, such as sulfur mustard (SM) and nitrogen mustard (NM), often
results in ocular surface damage. This can lead to the emergence of various corneal …

Sulfur mustard-induced ocular surface disorders

A Baradaran-Rafii, M Eslani, SCG Tseng - The ocular surface, 2011 - Elsevier
Sulfur mustard is a vesicant agent with severe irritating effects on living tissues, including
skin, mucous membranes, eyes, and respiratory tract. The eyes are the most susceptible …

Lipid keratopathy: a review of pathophysiology, differential diagnosis, and management

MGN Hall, M Moshirfar, A Amin-Javaheri… - Ophthalmology and …, 2020 - Springer
Lipid keratopathy is a disease in which fat deposits accumulate in the cornea, leading to
opacification and decrease of visual acuity. This condition can be idiopathic without signs of …

Management of mustard gas-induced limbal stem cell deficiency and keratitis

MA Javadi, MR Jafarinasab, S Feizi, F Karimian… - Ophthalmology, 2011 - Elsevier
PURPOSE: To report the clinical findings and compare outcomes of different surgical
techniques evolved over time in a large series of patients with delayed-onset mustard gas …

Pathogenesis of acute and delayed corneal lesions after ocular exposure to sulfur mustard vapor

P McNutt, T Hamilton, M Nelson, A Adkins, A Swartz… - Cornea, 2012 - journals.lww.com
Purpose: Sulfur mustard (SM) exposure results in dose-dependent morbidities caused by
cytotoxicity and vesication. Although lesions resulting from ocular exposure often resolve …

Mustard Gas Exposure Actuates SMAD2/3 Signaling to Promote Myofibroblast Generation in the Cornea

NR Sinha, R Tripathi, PK Balne, L Suleiman, K Simkins… - Cells, 2023 - mdpi.com
Sulfur mustard gas (SM) is a vesicating and alkylating agent used as a chemical weapon in
many mass-casualty incidents since World War I. Ocular injuries were reported in> 90% of …

Dose-dependent emergence of acute and recurrent corneal lesions in sulfur mustard-exposed rabbit eyes

PM McNutt, KEM Kelly, AC Altvater, MR Nelson… - Toxicology Letters, 2021 - Elsevier
Sulfur mustard (SM) is a lipid soluble alkylating agent that causes genotoxic injury. The eye
is highly sensitive to SM toxicity and exposures exceeding 400 mg min/m 3 can elicit …

Limbal stem cell deficiency (LSCD) in rats and mice following whole body exposure to sulfur mustard (SM) vapor

T Kadar, V Horwitz, M Cohen, I Egoz, H Gutman… - Experimental Eye …, 2022 - Elsevier
Ocular injuries following sulfur mustard (SM) exposure are characterized by an acute phase
expressed by corneal erosions and inflammation of the anterior segment that after a …