Sex and gender differences in myocarditis and dilated cardiomyopathy: an update

DL Fairweather, DJ Beetler, N Musigk… - Frontiers in …, 2023 - frontiersin.org
In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …

Sex differences in autoimmune disease from a pathological perspective

DL Fairweather, S Frisancho-Kiss, NR Rose - The American journal of …, 2008 - Elsevier
Autoimmune diseases affect∼ 8% of the population, 78% of whom are women. The reason
for the high prevalence in women is unclear. Women are known to respond to infection …

Molecular regulation of androgen action in prostate cancer

SM Dehm, DJ Tindall - Journal of cellular biochemistry, 2006 - Wiley Online Library
Androgens are critical regulators of prostate differentiation and function, as well as prostate
cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment …

Sex differences in inflammation during atherosclerosis

DL Fairweather - Clinical Medicine Insights: Cardiology, 2014 - journals.sagepub.com
Atherosclerosis is the leading cause of death in the United States and worldwide, yet more
men die from atherosclerosis than women, and at a younger age. Women, on the other …

[PDF][PDF] Antiinflammatory effect of androgen receptor activation in human benign prostatic hyperplasia cells

L Vignozzi, I Cellai, R Santi, L Lombardelli… - Journal of …, 2012 - academia.edu
Progression of benign prostatic hyperplasia (BPH) involves chronic inflammation and
immune dysregulation. Preclinical studies have demonstrated that prostate inflammation …

Androgen activation of the sterol regulatory element-binding protein pathway: Current insights

HV Heemers, G Verhoeven… - Molecular …, 2006 - academic.oup.com
The cellular effects of androgens are mediated by a cognate receptor, the androgen
receptor. Typically, the androgen receptor is viewed to exert its activity by binding to …

Combination therapy with a second-generation androgen receptor antagonist and a metastasis vaccine improves survival in a spontaneous prostate cancer model

A Ardiani, B Farsaci, CJ Rogers, A Protter, Z Guo… - Clinical Cancer …, 2013 - AACR
Purpose: Enzalutamide, a second-generation androgen antagonist, was approved by the
US Food and Drug Administration (FDA) for castration-resistant prostate cancer (CRPC) …

Androgen ablation augments prostate cancer vaccine immunogenicity only when applied after immunization

YT Koh, A Gray, SA Higgins, B Hubby, WM Kast - The Prostate, 2009 - Wiley Online Library
BACKGROUND Androgen ablation (AA) causes apoptosis of normal and neoplastic prostate
cells. It is a standard treatment for advanced prostate cancer. Androgen ablation‐mediated …

Expression, regulation and function of the ISGylation system in prostate cancer

A Kiessling, C Hogrefe, S Erb, C Bobach, S Fuessel… - Oncogene, 2009 - nature.com
The androgen receptor (AR) plays a crucial role in the modulation of prostate cell
proliferation and is involved in the development and progression of prostate cancer (PCa) …

[HTML][HTML] Proteinase and growth factor alterations revealed by gene microarray analysis of human diabetic corneas

M Saghizadeh, AA Kramerov, J Tajbakhsh… - … & visual science, 2005 - arvojournals.org
purpose. To identify proteinases and growth factors abnormally expressed in human
corneas of donors with diabetic retinopathy (DR), additional to previously described matrix …