Genetic Control of Muscle Diversification and Homeostasis: Insights from Drosophila

P Poovathumkadavil, K Jagla - Cells, 2020 - mdpi.com
In the fruit fly, Drosophila melanogaster, the larval somatic muscles or the adult thoracic flight
and leg muscles are the major voluntary locomotory organs. They share several …

[HTML][HTML] Mechanoresponsive regulation of myogenesis by the force-sensing transcriptional regulator Tono

X Zhang, J Avellaneda, ML Spletter, SB Lemke… - Current Biology, 2024 - cell.com
Muscle morphogenesis is a multi-step program, starting with myoblast fusion, followed by
myotube-tendon attachment and sarcomere assembly, with subsequent sarcomere …

Zasp52, a Core Z-disc Protein in Drosophila Indirect Flight Muscles, Interacts with α-Actinin via an Extended PDZ Domain

KA Liao, N González-Morales, F Schöck - PLoS genetics, 2016 - journals.plos.org
Z-discs are organizing centers that establish and maintain myofibril structure and function.
Important Z-disc proteins are α-actinin, which cross-links actin thin filaments at the Z-disc …

Dietary cadmium induced declined locomotory and reproductive fitness with altered homeostasis of essential elements in Drosophila melanogaster

KP Nanda, H Firdaus - Comparative Biochemistry and Physiology Part C …, 2022 - Elsevier
Cadmium (Cd) exerts detrimental effects on multiple biological processes of the living
organisms along with epigenetic transgenerational effect. Drosophila melanogaster offers …

Bruno 1/CELF regulates splicing and cytoskeleton dynamics to ensure correct sarcomere assembly in Drosophila flight muscles

E Nikonova, J DeCata, M Canela, C Barz, A Esser… - Plos …, 2024 - journals.plos.org
Muscles undergo developmental transitions in gene expression and alternative splicing that
are necessary to refine sarcomere structure and contractility. CUG-BP and ETR-3-like …

Functional redundancy and nonredundancy between two Troponin C isoforms in Drosophila adult muscles

MB Chechenova, S Maes, ST Oas… - Molecular biology of …, 2017 - Am Soc Cell Biol
We investigated the functional overlap of two muscle Troponin C (TpnC) genes that are
expressed in the adult fruit fly, Drosophila melanogaster: TpnC4 is predominantly expressed …

[PDF][PDF] Indirect flight muscles in Drosophila melanogaster as a tractable model to study muscle development and disease

S Jawkar, U Nongthomba - International Journal of …, 2020 - researchgate.net
Myogenesis is a complex multifactorial process leading to the formation of the adult muscle.
An amalgamation of autonomous processes including myoblast fusion and …

Overexpression of miRNA-9 Generates Muscle Hypercontraction Through Translational Repression of Troponin-T in Drosophila melanogaster Indirect Flight Muscles

P Katti, D Thimmaya, A Madan… - G3: Genes, Genomes …, 2017 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding endogenous RNAs, typically 21–23 nucleotides
long, that regulate gene expression, usually post-transcriptionally, by binding to the 3′-UTR …

RNAi‐mediated pest control targeting the Troponin I (wupA) gene in sweet potato weevil, Cylas formicarius

M Zhang, X Zhang, T Chen, Y Liao, B Yang… - Insect …, 2024 - Wiley Online Library
The sweet potato weevil (Cylas formicarius) is a critical pest producing enormous global
losses in sweet potato crops. Traditional pest management approaches for sweet potato …

A mechanically regulated liquid-liquid phase separation of the transcriptional regulator Tono instructs muscle development

X Zhang, J Avellaneda, ML Spletter, S Lemke… - bioRxiv, 2023 - biorxiv.org
Muscle morphogenesis is a multi-step program, starting with myoblast fusion, followed by
myotube-tendon attachment and sarcomere assembly, with subsequent sarcomere …