The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and
whose composition changes as a function of an animal's physiological state. Ciliated …

Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

An animal's nervous system changes as its body grows from birth to adulthood and its
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …

The spinal cord is home to the intrinsic networks for locomotion. An animal in which the
spinal cord has been fully severed from the brain can still produce rhythmic, patterned …

The mesencephalic locomotor region (MLR) is a brain stem area whose stimulation triggers
graded forward locomotion. How MLR neurons recruit downstream vsx2+(V2a) …

The flexibility of locomotor movements requires an accurate control of their start, duration,
and speed. How brainstem circuits encode and convey these locomotor parameters remains …

Here we design and optimize a genetically encoded fluorescent indicator, iAChSnFR, for the
ubiquitous neurotransmitter acetylcholine, based on a bacterial periplasmic binding protein …

Motor circuits develop in sequence from those governing fast movements to those governing
slow. Here we examine whether upstream sensory circuits are organized by similar …

Locomotion requires precise control of the strength and speed of muscle contraction and is
achieved by recruiting functionally distinct subtypes of motor neurons (MNs). MNs are …

Across the nervous system, neurons with similar attributes are topographically organized.
This topography reflects developmental pressures. Oddly, vestibular (balance) nuclei are …