Synthetic biology holds great promise for addressing global needs. However, most current
developments are not immediately translatable to 'outside-the-lab'scenarios that differ from …

In this review, we address recent advances made in pathway engineering, directed
evolution, and systems/synthetic biology approaches employed in the production and …

Polyketides represent an extremely diverse class of secondary metabolites often explored
for their bioactive traits. These molecules are also attractive building blocks for chemical …

Industrial biocatalysis is an economically attractive option for the production of valuable
chemicals. Our repertoire of cheap building blocks and commodity target molecules is vastly …

Covering: 2015 up to July 2021 The market for cosmetics is consumer driven and the desire
for green, sustainable and natural ingredients is increasing. The use of isolated enzymes …

Abstract α-Linolenic acid (ALA) is an essential ω-3 fatty with reported health benefits.
However, this molecule is naturally found in plants such as flaxseed and canola which …

Abstract Systems metabolic engineering faces the formidable task of rewiring microbial
metabolism to cost-effectively generate high-value molecules from a variety of inexpensive …

Highlights•The commonly used strategies to modify chassis microbes are
described.•Synthetic genomes, artificial ribosomes, unnatural base pairs, and expanded …

Synthetic biology is the repurposing of biological systems for novel objectives and
applications. Through the co-ordinated and balanced expression of genes, both native and …

Microbial lipids have been a hot topic in the field of metabolic engineering and synthetic
biology due to their increased market and important applications in biofuels, oleochemicals …