New vaccine technologies to combat outbreak situations
Ever since the development of the first vaccine more than 200 years ago, vaccinations have
greatly decreased the burden of infectious diseases worldwide, famously leading to the …
greatly decreased the burden of infectious diseases worldwide, famously leading to the …
A comparison of plasmid DNA and mRNA as vaccine technologies
MA Liu - Vaccines, 2019 - mdpi.com
This review provides a comparison of the theoretical issues and experimental findings for
plasmid DNA and mRNA vaccine technologies. While both have been under development …
plasmid DNA and mRNA vaccine technologies. While both have been under development …
A brief review on DNA vaccines in the era of COVID-19
This article provides a brief overview of DNA vaccines. First, the basic DNA vaccine design
strategies are described, then specific issues related to the industrial production of DNA …
strategies are described, then specific issues related to the industrial production of DNA …
Current state of Ebola virus vaccines: A snapshot
C Woolsey, TW Geisbert - PLoS pathogens, 2021 - journals.plos.org
Four species of the genus Ebolavirus cause severe and often lethal disease in humans:
Sudan ebolavirus (SUDV), Bundibugyo ebolavirus (BDBV), Taï Forest ebolavirus (TAFV) …
Sudan ebolavirus (SUDV), Bundibugyo ebolavirus (BDBV), Taï Forest ebolavirus (TAFV) …
Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials
Summary Background The Zika virus epidemic and associated congenital infections have
prompted rapid vaccine development. We assessed two new DNA vaccines expressing …
prompted rapid vaccine development. We assessed two new DNA vaccines expressing …
Pathogenicity and virulence of Marburg virus
Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …
Improved DNA vaccine delivery with needle-free injection systems
DNA vaccines have inherent advantages compared to other vaccine types, including safety,
rapid design and construction, ease and speed to manufacture, and thermostability …
rapid design and construction, ease and speed to manufacture, and thermostability …
Chimpanzee adenovirus vector Ebola vaccine
JE Ledgerwood, AD DeZure, DA Stanley… - … England Journal of …, 2017 - Mass Medical Soc
Background The unprecedented 2014 epidemic of Ebola virus disease (EVD) prompted an
international response to accelerate the availability of a preventive vaccine. A replication …
international response to accelerate the availability of a preventive vaccine. A replication …
Chemical and biological sensors for viral detection
Infectious diseases commonly occur in contaminated water, food, and bodily fluids and
spread rapidly, resulting in death of humans and animals worldwide. Among infectious …
spread rapidly, resulting in death of humans and animals worldwide. Among infectious …
Species-specific immunogenicity and protective efficacy of a vesicular stomatitis virus-based Sudan virus vaccine: a challenge study in macaques
A Marzi, P Fletcher, F Feldmann, G Saturday… - The Lancet …, 2023 - thelancet.com
Summary Background The recent Sudan virus (SUDV) outbreak in Uganda highlights the
need for rapid response capabilities, including development of vaccines against emerging …
need for rapid response capabilities, including development of vaccines against emerging …